The Diversity of Genetic Outcomes from CRISPR/Cas Gene Editing is Regulated by the Length of the Symmetrical Donor DNA Template

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas gene editing systems have enabled molecular geneticists to manipulate prokaryotic and eukaryotic genomes with greater efficiency and precision. CRISPR/Cas provides adaptive immunity in bacterial cells by degrading invading viral...

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Bibliographic Details
Main Authors: Amanda M. Hewes, Brett M. Sansbury, Eric B. Kmiec
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/10/1160