Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19

Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19

Summary: Despite the worldwide effect of the coronavirus disease 2019 (COVID-19) pandemic, the underlying mechanisms of fatal viral pneumonia remain elusive. Here, we show that critical COVID-19 is associated with enhanced eosinophil-mediated inflammation when compared to non-critical cases. In addi...

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Bibliographic Details
Main Authors: Dong-Min Kim, Yuri Kim, Jun-Won Seo, Jooyeon Lee, Uni Park, Na-Young Ha, Jaemoon Koh, Hyoree Park, Jae-Won Lee, Hyo-Jin Ro, Na Ra Yun, Da Young Kim, Sung Ho Yoon, Yong Sub Na, Do Sik Moon, Sung-Chul Lim, Choon-Mee Kim, Kyeongseok Jeon, Jun-Gu Kang, Na-Yoon Jang, Hyeongseok Jeong, Jungok Kim, Shinhyea Cheon, Kyung Mok Sohn, Jae Youg Moon, Sungmin Kym, Seung Ro Han, Myung-Shin Lee, Hyun-Je Kim, Woong-Yang Park, Ji-Yeob Choi, Hyun-Woo Shin, Hye-Young Kim, Chung-Hyun Cho, Yoon Kyung Jeon, Yeon-Sook Kim, Nam-Hyuk Cho
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Cell Reports
Subjects:
COVID-19
SARS-CoV-2
eosinophil
pneumonia
immune complex
complement
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721012584

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