Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital
Background: Diabetic ketoacidosis, a well-known and major acute metabolic complication classically occurs in young patients with type 1 diabetes. However, it may occur in patients with type 2 Diabetes Mellitus too. Objective: Aim of this study was to look into the clinical profile, precipitatin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2015-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/5995/8586_CE[Ra1]_F(P)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Background: Diabetic ketoacidosis, a well-known and major
acute metabolic complication classically occurs in young
patients with type 1 diabetes. However, it may occur in patients
with type 2 Diabetes Mellitus too.
Objective: Aim of this study was to look into the clinical profile,
precipitating factors and clinical outcome in the patients
presenting with Diabetic ketoacidosis in the Emergency of a
Tertiary care hospital.
Design: The study was a prospective study conducted over
a period of two years in Kasturba Medical College, Manipal
Karnataka, India.
Materials and Methods: Clinical profile of 60 diabetic patients
admitted in the Emergency with the diagnosis of Diabetic
ketoacidosis were analysed.
Results: Out of 60 patients, 12 were of Type 1 and 48 were
Type 2 Diabetes Mellitus. Mean duration of diabetes was 8.65
years. Only 14 (23.3%) patients were taking regular treatment
for Diabetes Mellitus whereas 32 (53.33%) patients were
on irregular treatment and eight (13.33%) were not on any
treatment at all. Among 12 Type 1 Diabetic patients, six patients
were freshly diagnosed to be diabetic when they presented
with Diabetic ketoacidosis complication. Nausea and vomiting
(63.33%) were the most common symptoms of these patients.
Infections (73.33%) were the most common precipitating factor
for Diabetic ketoacidosis. Mean fluid requirement on first day of
therapy was 3.51 liters. Mortality of 10% was seen.
Conclusion: Diabetic ketoacidosis is a fatal acute metabolic
complication of Diabetes Mellitus with heterogeneous clinical
presentation. Early diagnosis and treatment can avoid morbidity
& mortality. |
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| ISSN: | 2249-782X 0973-709X |