Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital
Background: Diabetic ketoacidosis, a well-known and major acute metabolic complication classically occurs in young patients with type 1 diabetes. However, it may occur in patients with type 2 Diabetes Mellitus too. Objective: Aim of this study was to look into the clinical profile, precipitatin...
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doaj-87f3953532dd4bda867c4eb36baeb6a72020-11-25T03:28:36ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-06-0196OC01OC0410.7860/JCDR/2015/8586.5995Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care HospitalPankaj Seth0Harpreet Kaur1Maneet Kaur2Assistant Professor, Department of Emergency Medicine, Dayanand Medical College and Hospital, Ludhiana, India.Assistant Professor, Department of Emergency Medicine, Dayanand Medical College and Hospital, Ludhiana, India.Assistant Professor, Department of Emergency Medicine, Dayanand Medical College and Hospital, Ludhiana, India.Background: Diabetic ketoacidosis, a well-known and major acute metabolic complication classically occurs in young patients with type 1 diabetes. However, it may occur in patients with type 2 Diabetes Mellitus too. Objective: Aim of this study was to look into the clinical profile, precipitating factors and clinical outcome in the patients presenting with Diabetic ketoacidosis in the Emergency of a Tertiary care hospital. Design: The study was a prospective study conducted over a period of two years in Kasturba Medical College, Manipal Karnataka, India. Materials and Methods: Clinical profile of 60 diabetic patients admitted in the Emergency with the diagnosis of Diabetic ketoacidosis were analysed. Results: Out of 60 patients, 12 were of Type 1 and 48 were Type 2 Diabetes Mellitus. Mean duration of diabetes was 8.65 years. Only 14 (23.3%) patients were taking regular treatment for Diabetes Mellitus whereas 32 (53.33%) patients were on irregular treatment and eight (13.33%) were not on any treatment at all. Among 12 Type 1 Diabetic patients, six patients were freshly diagnosed to be diabetic when they presented with Diabetic ketoacidosis complication. Nausea and vomiting (63.33%) were the most common symptoms of these patients. Infections (73.33%) were the most common precipitating factor for Diabetic ketoacidosis. Mean fluid requirement on first day of therapy was 3.51 liters. Mortality of 10% was seen. Conclusion: Diabetic ketoacidosis is a fatal acute metabolic complication of Diabetes Mellitus with heterogeneous clinical presentation. Early diagnosis and treatment can avoid morbidity & mortality. https://jcdr.net/articles/PDF/5995/8586_CE[Ra1]_F(P)_PF1(PAK)_PFA(AK)_PF2(PAG).pdfdiabetes mellitusemphysematous pyelonephritishyperglycaemiaketosisnon-compliance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pankaj Seth Harpreet Kaur Maneet Kaur |
spellingShingle |
Pankaj Seth Harpreet Kaur Maneet Kaur Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital Journal of Clinical and Diagnostic Research diabetes mellitus emphysematous pyelonephritis hyperglycaemia ketosis non-compliance |
author_facet |
Pankaj Seth Harpreet Kaur Maneet Kaur |
author_sort |
Pankaj Seth |
title |
Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital |
title_short |
Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital |
title_full |
Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital |
title_fullStr |
Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital |
title_full_unstemmed |
Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital |
title_sort |
clinical profile of diabetic ketoacidosis: a prospective study in a tertiary care hospital |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2015-06-01 |
description |
Background: Diabetic ketoacidosis, a well-known and major
acute metabolic complication classically occurs in young
patients with type 1 diabetes. However, it may occur in patients
with type 2 Diabetes Mellitus too.
Objective: Aim of this study was to look into the clinical profile,
precipitating factors and clinical outcome in the patients
presenting with Diabetic ketoacidosis in the Emergency of a
Tertiary care hospital.
Design: The study was a prospective study conducted over
a period of two years in Kasturba Medical College, Manipal
Karnataka, India.
Materials and Methods: Clinical profile of 60 diabetic patients
admitted in the Emergency with the diagnosis of Diabetic
ketoacidosis were analysed.
Results: Out of 60 patients, 12 were of Type 1 and 48 were
Type 2 Diabetes Mellitus. Mean duration of diabetes was 8.65
years. Only 14 (23.3%) patients were taking regular treatment
for Diabetes Mellitus whereas 32 (53.33%) patients were
on irregular treatment and eight (13.33%) were not on any
treatment at all. Among 12 Type 1 Diabetic patients, six patients
were freshly diagnosed to be diabetic when they presented
with Diabetic ketoacidosis complication. Nausea and vomiting
(63.33%) were the most common symptoms of these patients.
Infections (73.33%) were the most common precipitating factor
for Diabetic ketoacidosis. Mean fluid requirement on first day of
therapy was 3.51 liters. Mortality of 10% was seen.
Conclusion: Diabetic ketoacidosis is a fatal acute metabolic
complication of Diabetes Mellitus with heterogeneous clinical
presentation. Early diagnosis and treatment can avoid morbidity
& mortality. |
topic |
diabetes mellitus emphysematous pyelonephritis hyperglycaemia ketosis non-compliance |
url |
https://jcdr.net/articles/PDF/5995/8586_CE[Ra1]_F(P)_PF1(PAK)_PFA(AK)_PF2(PAG).pdf |
work_keys_str_mv |
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