REVIGO summarizes and visualizes long lists of gene ontology terms.
Outcomes of high-throughput biological experiments are typically interpreted by statistical testing for enriched gene functional categories defined by the Gene Ontology (GO). The resulting lists of GO terms may be large and highly redundant, and thus difficult to interpret.REVIGO is a Web server tha...
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doaj-8810d369a0334ac7a815bb512de201a82020-11-25T00:11:17ZengPublic Library of Science (PLoS)PLoS ONE1932-62032011-01-0167e2180010.1371/journal.pone.0021800REVIGO summarizes and visualizes long lists of gene ontology terms.Fran SupekMatko BošnjakNives ŠkuncaTomislav ŠmucOutcomes of high-throughput biological experiments are typically interpreted by statistical testing for enriched gene functional categories defined by the Gene Ontology (GO). The resulting lists of GO terms may be large and highly redundant, and thus difficult to interpret.REVIGO is a Web server that summarizes long, unintelligible lists of GO terms by finding a representative subset of the terms using a simple clustering algorithm that relies on semantic similarity measures. Furthermore, REVIGO visualizes this non-redundant GO term set in multiple ways to assist in interpretation: multidimensional scaling and graph-based visualizations accurately render the subdivisions and the semantic relationships in the data, while treemaps and tag clouds are also offered as alternative views. REVIGO is freely available at http://revigo.irb.hr/.http://europepmc.org/articles/PMC3138752?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fran Supek Matko Bošnjak Nives Škunca Tomislav Šmuc |
spellingShingle |
Fran Supek Matko Bošnjak Nives Škunca Tomislav Šmuc REVIGO summarizes and visualizes long lists of gene ontology terms. PLoS ONE |
author_facet |
Fran Supek Matko Bošnjak Nives Škunca Tomislav Šmuc |
author_sort |
Fran Supek |
title |
REVIGO summarizes and visualizes long lists of gene ontology terms. |
title_short |
REVIGO summarizes and visualizes long lists of gene ontology terms. |
title_full |
REVIGO summarizes and visualizes long lists of gene ontology terms. |
title_fullStr |
REVIGO summarizes and visualizes long lists of gene ontology terms. |
title_full_unstemmed |
REVIGO summarizes and visualizes long lists of gene ontology terms. |
title_sort |
revigo summarizes and visualizes long lists of gene ontology terms. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2011-01-01 |
description |
Outcomes of high-throughput biological experiments are typically interpreted by statistical testing for enriched gene functional categories defined by the Gene Ontology (GO). The resulting lists of GO terms may be large and highly redundant, and thus difficult to interpret.REVIGO is a Web server that summarizes long, unintelligible lists of GO terms by finding a representative subset of the terms using a simple clustering algorithm that relies on semantic similarity measures. Furthermore, REVIGO visualizes this non-redundant GO term set in multiple ways to assist in interpretation: multidimensional scaling and graph-based visualizations accurately render the subdivisions and the semantic relationships in the data, while treemaps and tag clouds are also offered as alternative views. REVIGO is freely available at http://revigo.irb.hr/. |
url |
http://europepmc.org/articles/PMC3138752?pdf=render |
work_keys_str_mv |
AT fransupek revigosummarizesandvisualizeslonglistsofgeneontologyterms AT matkobosnjak revigosummarizesandvisualizeslonglistsofgeneontologyterms AT nivesskunca revigosummarizesandvisualizeslonglistsofgeneontologyterms AT tomislavsmuc revigosummarizesandvisualizeslonglistsofgeneontologyterms |
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