Exploring Antiparasitic Molecule Sources from Timber by-Product Industries—Leishmanicidal and Trypanocidal Compounds from Clathrotropis brunnea Amshoff

Exploring Antiparasitic Molecule Sources from Timber by-Product Industries—Leishmanicidal and Trypanocidal Compounds from Clathrotropis brunnea Amshoff

Through bioguided in vitro assays, the leishmanicidal and trypanocidal effects of an ethanol extract, seven fractions, and two pure substances obtained from Clathrotropis brunnea Amshoff sawdust were established. The effectiveness of the two metabolites was confirmed in a hamster model of cutaneous...

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Bibliographic Details
Main Authors: Fernando Torres, Sara M. Robledo, Wiston Quiñones, Gustavo Escobar, Rosendo Archbold, Edwin Correa, Juan Fernando Gil, Natalia Arbeláez, Javier Murillo, Fernando Echeverri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
antiparasite bioguided search
leishmanicidal and trypanocidal
animal model assays
flavanone and stilbene compounds
timber by-products
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.584668/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.584668/full

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