Liver resection for atypical giant focal nodular hyperplasia
Focal nodular hyperplasia (FNH) usually presents in children with underlying liver disease, in patients undergone chemotherapy and adolescent females. The reports, describing huge FNH with severe dilatation of the right hepatic vein (RHV) in healthy children are absent.A 2,7 years old boy without an...
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doaj-88816bcd6f23408eaf9bcc8738bf07922020-11-25T01:09:08ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662019-08-0147Liver resection for atypical giant focal nodular hyperplasiaDmitry Akhaladze0Nikolay Grachev1Denis Kachanov2Sergey Talypov3Nikolay Merkulov4Natalia Uskova5Evgeniy Andreev6Gavriil Rabaev7Natalia Ivanova8Svetlana Varfolomeeva9Department of Oncology and Pediatric Surgery of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, Russia; Corresponding author.Department of Oncology and Pediatric Surgery of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaDepartment of Clinical Oncology of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaDepartment of Oncology and Pediatric Surgery of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaDepartment of Oncology and Pediatric Surgery of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaDepartment of Oncology and Pediatric Surgery of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaDepartment of Oncology and Pediatric Surgery of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaDepartment of Oncology and Pediatric Surgery of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaDepartment of Oncology and Pediatric Surgery of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaInstitute of Oncology, Radiology and Nuclear Medicine of Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, 1 Samory Mashela Str., 117997, Moscow, RussiaFocal nodular hyperplasia (FNH) usually presents in children with underlying liver disease, in patients undergone chemotherapy and adolescent females. The reports, describing huge FNH with severe dilatation of the right hepatic vein (RHV) in healthy children are absent.A 2,7 years old boy without any comorbidities was presented with intermittent abdominal pain and a huge mass, causing the abdominal asymmetry. The initial imaging showed the giant mass (more than 125 mm in the biggest dimensions), with sings of the atypical FNH It was arising from 5,6 liver segments, and was accompanied with strong expansion of the RHV. According to CT-volumetry, the lesion volume exceeded the right hepatic lobe volume on 350 ml. Despite the all signs of atypical FNH and absence of underlying liver diseases, the surgery without preoperative biopsy was carried out. Postoperative course was uneventful. The pathological examination confirmed the diagnosis - focal nodular hyperplasia of the liver. The postoperative computed tomography showed the RHV, returned to its physiological size.Giant atypical FNH may occur in very young children. Huge size of the tumor can lead to severe dilatation of the RHV, which can be reversible. The surgical resection is the treatment of choice in such cases. Keywords: Huge focal nodular hyperplasia, Children, Liver resection, Hepatic vein dilatationhttp://www.sciencedirect.com/science/article/pii/S2213576619300351 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dmitry Akhaladze Nikolay Grachev Denis Kachanov Sergey Talypov Nikolay Merkulov Natalia Uskova Evgeniy Andreev Gavriil Rabaev Natalia Ivanova Svetlana Varfolomeeva |
spellingShingle |
Dmitry Akhaladze Nikolay Grachev Denis Kachanov Sergey Talypov Nikolay Merkulov Natalia Uskova Evgeniy Andreev Gavriil Rabaev Natalia Ivanova Svetlana Varfolomeeva Liver resection for atypical giant focal nodular hyperplasia Journal of Pediatric Surgery Case Reports |
author_facet |
Dmitry Akhaladze Nikolay Grachev Denis Kachanov Sergey Talypov Nikolay Merkulov Natalia Uskova Evgeniy Andreev Gavriil Rabaev Natalia Ivanova Svetlana Varfolomeeva |
author_sort |
Dmitry Akhaladze |
title |
Liver resection for atypical giant focal nodular hyperplasia |
title_short |
Liver resection for atypical giant focal nodular hyperplasia |
title_full |
Liver resection for atypical giant focal nodular hyperplasia |
title_fullStr |
Liver resection for atypical giant focal nodular hyperplasia |
title_full_unstemmed |
Liver resection for atypical giant focal nodular hyperplasia |
title_sort |
liver resection for atypical giant focal nodular hyperplasia |
publisher |
Elsevier |
series |
Journal of Pediatric Surgery Case Reports |
issn |
2213-5766 |
publishDate |
2019-08-01 |
description |
Focal nodular hyperplasia (FNH) usually presents in children with underlying liver disease, in patients undergone chemotherapy and adolescent females. The reports, describing huge FNH with severe dilatation of the right hepatic vein (RHV) in healthy children are absent.A 2,7 years old boy without any comorbidities was presented with intermittent abdominal pain and a huge mass, causing the abdominal asymmetry. The initial imaging showed the giant mass (more than 125 mm in the biggest dimensions), with sings of the atypical FNH It was arising from 5,6 liver segments, and was accompanied with strong expansion of the RHV. According to CT-volumetry, the lesion volume exceeded the right hepatic lobe volume on 350 ml. Despite the all signs of atypical FNH and absence of underlying liver diseases, the surgery without preoperative biopsy was carried out. Postoperative course was uneventful. The pathological examination confirmed the diagnosis - focal nodular hyperplasia of the liver. The postoperative computed tomography showed the RHV, returned to its physiological size.Giant atypical FNH may occur in very young children. Huge size of the tumor can lead to severe dilatation of the RHV, which can be reversible. The surgical resection is the treatment of choice in such cases. Keywords: Huge focal nodular hyperplasia, Children, Liver resection, Hepatic vein dilatation |
url |
http://www.sciencedirect.com/science/article/pii/S2213576619300351 |
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