CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes.

CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes.

Neutrophil extracellular traps (NETs) evolved as a unique effector mechanism contributing to resistance against infection that can also promote tissue damage in inflammatory conditions. Malaria infection can trigger NET release, but the mechanisms and consequences of NET formation in this context re...

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Bibliographic Details
Main Authors: Danielle A S Rodrigues, Elisa B Prestes, Andreza M S Gama, Leandro de Souza Silva, Ana Acácia S Pinheiro, Jose Marcos C Ribeiro, Raquel M P Campos, Pedro M Pimentel-Coelho, Heitor S De Souza, Alassane Dicko, Patrick E Duffy, Michal Fried, Ivo M B Francischetti, Elvira M Saraiva, Heitor A Paula-Neto, Marcelo T Bozza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008230

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