Structural Modification of Nanomicelles through Phosphatidylcholine: The Enhanced Drug-Loading Capacity and Anticancer Activity of Celecoxib-Casein Nanoparticles for the Intravenous Delivery of Celecoxib

Structural Modification of Nanomicelles through Phosphatidylcholine: The Enhanced Drug-Loading Capacity and Anticancer Activity of Celecoxib-Casein Nanoparticles for the Intravenous Delivery of Celecoxib

This study aims to stabilize loaded celecoxib (CX) by modifying the structure of casein nanoparticles through phosphatidylcholine. The results show that Egg yolk phosphatidylcholine PC<sub>98T</sub> (PC) significantly increased the stability of CX-PC-casein nanoparticles (NPs) (192.6 nm)...

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Bibliographic Details
Main Authors: Liuli Xv, Xinxin Qian, Yan Wang, Chenghuan Yu, Dingkui Qin, Yahui Zhang, Peng Jin, Qizhen Du
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Nanomaterials
Subjects:
celecoxib
delivery
casein nanoparticles
stability
anticancer
Online Access:https://www.mdpi.com/2079-4991/10/3/451

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