Rotavirus replication in the cholangiocyte mediates the temporal dependence of murine biliary atresia.

Biliary atresia (BA) is a neonatal disease that results in obliteration of the biliary tree. The murine model of BA, which mirrors the human disease, is based upon infection of newborn mice with rhesus rotavirus (RRV), leading to an obstructive cholangiopathy. The purpose of this study was to charac...

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Bibliographic Details
Main Authors: Sujit K Mohanty, Bryan Donnelly, Alexander Bondoc, Mubeen Jafri, Ashley Walther, Abigail Coots, Monica McNeal, David Witte, Gregory M Tiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3700947?pdf=render