microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function

microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function

Objectives: Hepatic insulin resistance is a hallmark of type 2 diabetes and obesity. Insulin receptor signaling through AKT and FOXO has important metabolic effects that have traditionally been ascribed to regulation of gene expression. However, whether all the metabolic effects of FOXO arise from i...

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Bibliographic Details
Main Authors: Fanny Langlet, Marcel Tarbier, Rebecca A. Haeusler, Stefania Camastra, Eleuterio Ferrannini, Marc R. Friedländer, Domenico Accili
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877818307543

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http://www.sciencedirect.com/science/article/pii/S2212877818307543

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