The relationship between biochemical parameters, interleukin-6 and ovarian morphology in polycystic ovary syndrome
Objectives: The aim of this study is to investigate relationshipsbetween biochemical parameters and interleukin-6 according to the ovarian morphology in polycysticovary syndrome (PCOS).Materials and methods: Total of 85 patients with PCOSwere divided into three groups according to the ultrasonograph...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Modestum Publishing LTD
2012-09-01
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| Series: | Journal of Clinical and Experimental Investigations |
| Subjects: | |
| Online Access: | http://jceionline.org/upload/sayi/10/JCEI-00313.pdf |
| Summary: | Objectives: The aim of this study is to investigate relationshipsbetween biochemical parameters and interleukin-6 according to the ovarian morphology in polycysticovary syndrome (PCOS).Materials and methods: Total of 85 patients with PCOSwere divided into three groups according to the ultrasonographicexamination of the ovaries; group 1 (with no polycysticimage at any of the ovaries, n=22), group 2 (withpolycystic image at only one ovary, n=41), and group 3(with polycystic image at both of the ovaries, n=22). Seruminterleukin 6 (IL-6), hormone levels, and homeostasismodel assessment-insulin resistance (HOMA-IR) weremeasured.Results: The mean serum IL-6 levels for groups 1, 2and 3 were 14.65 ± 6.18 pg/mL, 16.22 ± 6.55 pg/mL, and14:53 ± 7.32 pg/mL, respectively. There was no staticallydifference between three groups for serum IL-6 levels(p>0.05). For metabolic profile, the mean of HOMA-IRwas 3.09±1.56 for group 2 and this was significantly lowerthan other groups (p<0.05).Conclusions: There were no difference in hormonal andinflammatory markers according to the ovarian morphologyin PCOS patients based on data derived form ourstudy. J Clin Exp Invest 2012; 3(3): 307-312Key words: PCOS, interleukin-6, ovarian morphology. |
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| ISSN: | 1309-8578 1309-6621 |