Effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers

• Main Authors: Lurdete Maria Rocha Gauch, Fabíola Silveira-Gomes, Renata Antunes Esteves, Simone Soares Pedrosa, Ely Simone Cajueiro Gurgel, Alberto Cardoso Arruda, Silvia Helena Marques-da-Silva
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2014-06-01
• Series: Revista da Sociedade Brasileira de Medicina Tropical
• Subjects: Candida albicans; Germ Tube; Rosmarinus officinalis
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300389&lng=en&tlng=en

Introduction The aim of this study was to investigate the effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Methods Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or without 4% R. officinalis essential oil. Results The essential oil from R. officinalis completely inhibited germ tube formation in the investigated C. albicans isolates. Conclusions The results demonstrate that the essential oil of R. officinalis modulates C. albicans pathogenicity through its primary virulence factor (i.e., germ tube formation was suppressed).