Changes in glomerular filtration rate and clinical course after sequential doses of carboplatin in children with embryonal brain tumors undergoing autologous stem cell transplantation

Changes in glomerular filtration rate and clinical course after sequential doses of carboplatin in children with embryonal brain tumors undergoing autologous stem cell transplantation

Abstract Background Treatment for malignant embryonal brain tumors in young children usually employs cycles of standardly dosed cisplatinum followed by high-dose carboplatinum-containing conditioning with single or tandem autologous stem cell rescue (HDC-ASCR). High-dose carboplatin is potentially n...

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Bibliographic Details
Main Authors: Yasser Elborai, Mohammad Almutereen, Ossama M. Maher, Hanafy Hafez, Michelle A. Lee, Leslie Lehmann
Format: Article
Language:English
Published: SpringerOpen 2020-02-01
Series:Journal of the Egyptian National Cancer Institute
Subjects:
Carboplatin
Brain tumor
GFR
Renal toxicity
Autologous stem cell transplant (ASCT)
Online Access:http://link.springer.com/article/10.1186/s43046-020-00024-6

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