The impact of laronidase treatment in otolaryngological manifestations of patients with mucopolysaccharidosis

The impact of laronidase treatment in otolaryngological manifestations of patients with mucopolysaccharidosis

ABSTRACT INTRODUCTION: Mucopolysaccharidosis (MPS) is a lysosomal storage disease caused by deficiency of a-l-iduronidase. The otolaryngological findings include hearing loss, otorrhea, recurrent otitis, hypertrophy of tonsils and adenoid, recurrent rhinosinusitis, speech disorders, snoring, oral b...

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Bibliographic Details
Main Authors: Ana Paula Fiuza Funicello Dualibi, Ana Maria Martins, Gustavo Antônio Moreira, Marisa Frasson de Azevedo, Reginaldo Raimundo Fujita, Shirley Shizue Nagata Pignatari
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Otorhinolaryngology
Subjects:
Mucopolysaccharidosis I
Laronidase
Enzymatic replacement therapy
URT infections
Sleep apnea
Hearing loss
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942016000500522&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942016000500522&lng=en&tlng=en

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