GNAQ Q209R Mutations Are Highly Specific for Circumscribed Choroidal Hemangioma

GNAQ Q209R Mutations Are Highly Specific for Circumscribed Choroidal Hemangioma

Several tumors, including uveal melanoma, show somatic mutations of <i>GNAQ/GNA11</i>. Circumscribed choroidal hemangioma is a benign tumor that becomes symptomatic in adulthood. In some patients, morphologic examination of biopsies is required for differential diagnosis between amelanot...

Full description

Bibliographic Details
Main Authors:	Claudia Helga Dorothee Le Guin, Klaus Alfred Metz, Stefan Horst Kreis, Nikolaos Emmanouel Bechrakis, Norbert Bornfeld, Michael Zeschnigk, Dietmar Rudolf Lohmann
Format:	Article
Language:	English
Published:	MDPI AG 2019-07-01
Series:	Cancers
Subjects:	circumscribed choroidal hemangioma GNAQ GNA11 oncogenic mutation biopsy
Online Access:	https://www.mdpi.com/2072-6694/11/7/1031

Similar Items

Choroidal Hemangioma Associated with Hepatic Hemangioma: A Case Report and Literature Review
by: Ana Boned-Murillo, et al.
Published: (2021-05-01)

Circumscribed choroidal hemangioma
by: Saeed Karimi, et al.
Published: (2015-01-01)

Oral Propranolol for Circumscribed Choroidal Hemangioma
by: Empar Sanz-Marco, et al.
Published: (2011-02-01)

Vitrectomy for circumscribed choroidal hemangioma with exudative retinal detachment refractory to transpupillary thermotherapy
by: Shukla Dhananjay, et al.
Published: (2007-01-01)

Lack of GNAQ and GNA11 germ-line mutations in familial melanoma pedigrees with uveal melanoma or blue nevi
by: Jason Ezra Hawkes, et al.
Published: (2013-06-01)

Circumscribed choroidal hemangioma: A case report and literature review
by: Morgan Berry, et al.
Published: (2017-04-01)

Effect of photodynamic therapy combined with intravitreal ranibizumab injection on circumscribed choroidal hemangioma
by: Yu-Shun Xue, et al.
Published: (2017-02-01)

Early detection of metastatic uveal melanoma by the analysis of tumor‐specific mutations in cell‐free plasma DNA
by: Claudia H. D. Le Guin, et al.
Published: (2021-09-01)

Treatment of circumscribed choroidal hemangioma: thermotherapy or brachytherapy. A comparative analysis
by: A. A. Yarovoy, et al.
Published: (2020-01-01)

Clinical therapeutic effect of two therapies on circumscribed choroidal hemangioma
by: Le-Le Huang, et al.
Published: (2014-03-01)

Comparison of outcomes between overlapping-spot and single-spot photodynamic therapy for circumscribed choroidal hemangioma
by: Zhao-An Su, et al.
Published: (2014-02-01)

Circumscribed Choroidal Hemangioma in a Chinese Patient Treated using Transpupillary Thermotherapy: A Case Report
by: Jia-Kang Wang, et al.
Published: (2005-09-01)

High-dose ruthenium-106 plaque therapy for circumscribed choroidal hemangioma: a retrospective study of 25 Chinese patients
by: Jing Li, et al.
Published: (2020-03-01)

Uveal melanoma: epidemiology, etiology, and treatment of primary disease
by: Krantz BA, et al.
Published: (2017-01-01)

Molecular and genetic diversity in melanoma of eye
by: N. N. Mazurenko, et al.
Published: (2018-11-01)

GNAQ knockdown promotes bone metastasis through epithelial-mesenchymal transition in lung cancer cells
by: Ji-Yoon Choi, et al.
Published: (2021-05-01)

Sturge-Weber Syndrome Linked to GNAQ Mutation
by: J Gordon Millichap
Published: (2013-07-01)

Malignant circumscribed acral hypokeratosis
by: Lorin A. Bibb, MD, et al.
Published: (2020-03-01)

Chinese medicine, Gui Lu Er Xian Jiao – related serous retinal detachment 2nd to circumscribed choroidal hemangioma a case report
by: Hsin Hui Huang, et al.
Published: (2021-09-01)

GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells
by: Helena Pópulo, et al.
Published: (2013-07-01)

Choroidal neovascular membrane in a treated choroidal hemangioma
by: Chokkahalli K Nagesha, et al.
Published: (2016-01-01)

Association of clinical, instrumental and molecular genetic predictors with the risk of development and tumor progression of melanocytic intraocular neoplasms
by: S. V. Saakyan, et al.
Published: (2020-12-01)

Modalidades de tratamiento para el hemangioma coroideo circunscrito Therapeutic modalities for circumscribed choroidal hemangioma
by: Caridad Chiang Rodríguez, et al.
Published: (2010-01-01)

Effects of oral propranolol for circumscribed choroidal hemangioma
by: Karlos Frederico Castelo Branco Sancho, et al.

circGNAQ, a circular RNA enriched in vascular endothelium, inhibits endothelial cell senescence and atherosclerosis progression
by: Wei-peng Wu, et al.
Published: (2021-12-01)

Circumscribed palmar hypokeratosis: Report of 2 new Ecuadorian cases, dermatoscopic description and brief literature review
by: Enrique Uraga, et al.
Published: (2016-07-01)

Our Treatment Results of Circumscribed and Diffuse Choroidal Hemangiomas
by: Esra Savku, et al.
Published: (2013-08-01)

Circumscribed choroidal hemangioma: An overview of clinical manifestation, diagnosis and management
by: Mrittika Sen, et al.
Published: (2019-01-01)

Understanding the structural changes following photodynamic and transpupillary thermotherapy for choroidal hemangioma using optical coherence tomography and optical coherence tomography angiography
by: Vishal Raval, et al.
Published: (2019-01-01)

Trametinib Induces the Stabilization of a Dual <i>GNAQ</i> p.Gly48Leu- and <i>FGFR4</i> p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized Oncology
by: Fanny S. Krebs, et al.
Published: (2020-10-01)

Rotating Supporting Hyperplanes and Snug Circumscribing Simplexes
by: Salmani Jajaei, Ghasemali
Published: (2018)

Circumscribed Storiform Collagenoma Associated with Rubinstein-Taybi Syndrome in a Young Adolescent
by: Nick Zavras, et al.
Published: (2016-03-01)

Treatment of circumscribed choroidal hemangioma using CyberKnife: A viable alternative
by: Aditi Agarwal, et al.
Published: (2019-01-01)

Optical coherence tomography angiography of circumscribed choroidal hemangioma treated with photodynamic therapy
by: Giuseppe Lo Giudice, et al.
Published: (2017-01-01)

New Type Modelling of the Circumscribed Self-Excited Spherical Attractor
by: Akgül, A., et al.
Published: (2022)

A few of my favorite things: circumscribed interests in autism are not accompanied by increased attentional salience on a personalized selective attention task
by: Owen E. Parsons, et al.
Published: (2017-04-01)

Circumscribed Interest Modulates Attention to Eyes in Boys With and Without Autism Spectrum Disorder
by: Qiandong Wang, et al.
Published: (2021-07-01)

Intravitreal bevacizumab (avastin) for circumscribed choroidal hemangioma
by: Subrata Mandal, et al.
Published: (2011-01-01)

Visual Search for Circumscribed Interests in Autism Is Similar to That of Neurotypical Individuals
by: Benjamin M. Silver, et al.
Published: (2020-10-01)

Altered reward system reactivity for personalized circumscribed interests in autism
by: Gregor Kohls, et al.
Published: (2018-01-01)