Ameliorating the Fibrotic Remodeling of the Heart through Direct Cardiac Reprogramming

Coronary artery disease is the most common form of cardiovascular diseases, resulting in the loss of cardiomyocytes (CM) at the site of ischemic injury. To compensate for the loss of CMs, cardiac fibroblasts quickly respond to injury and initiate cardiac remodeling in an injured heart. In the remode...

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Bibliographic Details
Main Authors: Emre Bektik, Ji-dong Fu
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/7/679