Association of manganese superoxide dismutase gene polymorphism (Ala-9Val) and breast cancer in males and females Associação do polimorfismo do gene da superóxido dismutase dependente de manganês (Ala-9Val) em homens e mulheres com câncer de mama

Association of manganese superoxide dismutase gene polymorphism (Ala-9Val) and breast cancer in males and females Associação do polimorfismo do gene da superóxido dismutase dependente de manganês (Ala-9Val) em homens e mulheres com câncer de mama

INTRODUCTION: One of the several metabolic pathways involved in breast carcinogenesis is the human polymorphism in the mitochondrial targeting sequence Ala-9Val of the manganese superoxide dismutase (MnSOD) gene, which has been previously associated with increased risk of breast cancer in females. S...

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Bibliographic Details
Main Authors: Claudia Giuliano Bica, Ivana Beatrice Mânica da Cruz, Leonardo Leiria de Moura da Silva, Nadima Vieira Toscani, Cláudio Galleano Zettler, Márcia Silveira Graudenz
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2007-06-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
Câncer de mama em homens
MnSOD
Polimorfismo gênico
SOD2
Estresse oxidativo
Male breast cancer
Gene polymorphism
Oxidative stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442007000300012

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