Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?

• Main Authors: Samira Saraya, Lamia Adel, Asmaa Mahmoud
• Format: Article
• Language: English
• Published: SpringerOpen 2017-06-01
• Series: The Egyptian Journal of Radiology and Nuclear Medicine
• Subjects: Breast cancer; Full field digital mammography; Contrast enhanced digital mammography; BIRADS 3 and 4
• Online Access: http://www.sciencedirect.com/science/article/pii/S0378603X17300529

Objective: To assess the efficiency of dual energy contrast enhanced mammography in the assessment of the indeterminate breast lesions (BIRADS 3 and BIRADS 4). Materials and methods: 34 female having 39 indeterminate breast lesions (BIRADS 3 and BIRADS 4) by digital mammography were further examined by dual energy contrast enhanced mammography. Two images were acquired at low and high energy in MLO view after 2 min and in CC view at 4 min post iodinated contrast injection (1.5 ml/kg with flow of 4 ml/s). Images were processed to obtain subtracted images to enhance the areas of the contrast uptake. Results: Results from pathology were detected for all cases. Contrast enhanced digital mammography showed specificity, sensitivity, PPV, NPV, FDR, FPR and accuracy of 93.75%, 91.3%, 88.2%, 95.4%, 11.7%, 8.6% and 92.3% respectively compared to full field digital mammography which were 68.75%, 69.5%, 61.1%, 76.1%, 38.8%, 30% and 69.2% respectively. Conclusion: Contrast-enhanced digital mammography is a useful tool to be used for breast cancer detection especially in indeterminate lesions (BIRADS 3 and 4).