Diversity of Bacteria Exhibiting Bile Acid-inducible 7α-dehydroxylation Genes in the Human Gut
The secondary bile acids deoxycholic acid (DCA) and lithocholic acid (LCA), formed by gut microbiota from primary bile acids via a multi-step 7α-dehydroxylation reaction, have wide-ranging effects on host metabolism and play an important role in health and disease. A few 7α-dehydroxylating strains h...
Main Authors: | Marius Vital, Tatjana Rud, Silke Rath, Dietmar H. Pieper, Dirk Schlüter |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Computational and Structural Biotechnology Journal |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037019302235 |
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