Cloud Services for Patient Cohort Identification Using the Informatics for Integrating Biology and the Bedside Platform

Despite the widespread use of the “Informatics for Integrating Biology and the Bedside” (i2b2) platform, there are substantial challenges for loading electronic health records (EHR) into i2b2 and for querying i2b2. We have previously presented a simplified framework for semantic abstraction of EHR r...

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Main Authors: Kavishwar B. Wagholikar, Shreekanth V. Joshi, Vishal V. Pai Vernekar, Yuri Ostrovsky, Somnath D. Desai, Pooja B. Magdum, Sachin B. Wakle, Sheetal Jain, Akshay Zagade, Rahul Patel, Shawn N. Murphy
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/2851713
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spelling doaj-89a5f4846f7f452cb64edd7632099d442020-11-25T03:45:54ZengHindawi LimitedBioMed Research International2314-61332314-61412020-01-01202010.1155/2020/28517132851713Cloud Services for Patient Cohort Identification Using the Informatics for Integrating Biology and the Bedside PlatformKavishwar B. Wagholikar0Shreekanth V. Joshi1Vishal V. Pai Vernekar2Yuri Ostrovsky3Somnath D. Desai4Pooja B. Magdum5Sachin B. Wakle6Sheetal Jain7Akshay Zagade8Rahul Patel9Shawn N. Murphy10Harvard Medical School, Boston, MA, USAPersistent Systems, Pune, IndiaPersistent Systems, Pune, IndiaPersistent Systems, Pune, IndiaPersistent Systems, Pune, IndiaPersistent Systems, Pune, IndiaPersistent Systems, Pune, IndiaPersistent Systems, Pune, IndiaPersistent Systems, Pune, IndiaPersistent Systems, Pune, IndiaHarvard Medical School, Boston, MA, USADespite the widespread use of the “Informatics for Integrating Biology and the Bedside” (i2b2) platform, there are substantial challenges for loading electronic health records (EHR) into i2b2 and for querying i2b2. We have previously presented a simplified framework for semantic abstraction of EHR records into i2b2. Building on our previous work, we have created a proof-of-concept implementation of cloud services on an i2b2 data store for cohort identification. Specifically, we have implemented a graphical user interface (GUI) that declares the key components for data import, transformation, and query of EHR data. The GUI integrates with Azure cloud services to create data pipelines for importing EHR data into i2b2, creation of derived facts, and querying for generating Sankey-like flow diagrams that characterize the patient cohorts. We have evaluated the implementation using the real-world MIMIC-III dataset. We discuss the key features of this implementation and direction for future work, which will advance the efforts of the research community for patient cohort identification.http://dx.doi.org/10.1155/2020/2851713
collection DOAJ
language English
format Article
sources DOAJ
author Kavishwar B. Wagholikar
Shreekanth V. Joshi
Vishal V. Pai Vernekar
Yuri Ostrovsky
Somnath D. Desai
Pooja B. Magdum
Sachin B. Wakle
Sheetal Jain
Akshay Zagade
Rahul Patel
Shawn N. Murphy
spellingShingle Kavishwar B. Wagholikar
Shreekanth V. Joshi
Vishal V. Pai Vernekar
Yuri Ostrovsky
Somnath D. Desai
Pooja B. Magdum
Sachin B. Wakle
Sheetal Jain
Akshay Zagade
Rahul Patel
Shawn N. Murphy
Cloud Services for Patient Cohort Identification Using the Informatics for Integrating Biology and the Bedside Platform
BioMed Research International
author_facet Kavishwar B. Wagholikar
Shreekanth V. Joshi
Vishal V. Pai Vernekar
Yuri Ostrovsky
Somnath D. Desai
Pooja B. Magdum
Sachin B. Wakle
Sheetal Jain
Akshay Zagade
Rahul Patel
Shawn N. Murphy
author_sort Kavishwar B. Wagholikar
title Cloud Services for Patient Cohort Identification Using the Informatics for Integrating Biology and the Bedside Platform
title_short Cloud Services for Patient Cohort Identification Using the Informatics for Integrating Biology and the Bedside Platform
title_full Cloud Services for Patient Cohort Identification Using the Informatics for Integrating Biology and the Bedside Platform
title_fullStr Cloud Services for Patient Cohort Identification Using the Informatics for Integrating Biology and the Bedside Platform
title_full_unstemmed Cloud Services for Patient Cohort Identification Using the Informatics for Integrating Biology and the Bedside Platform
title_sort cloud services for patient cohort identification using the informatics for integrating biology and the bedside platform
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2020-01-01
description Despite the widespread use of the “Informatics for Integrating Biology and the Bedside” (i2b2) platform, there are substantial challenges for loading electronic health records (EHR) into i2b2 and for querying i2b2. We have previously presented a simplified framework for semantic abstraction of EHR records into i2b2. Building on our previous work, we have created a proof-of-concept implementation of cloud services on an i2b2 data store for cohort identification. Specifically, we have implemented a graphical user interface (GUI) that declares the key components for data import, transformation, and query of EHR data. The GUI integrates with Azure cloud services to create data pipelines for importing EHR data into i2b2, creation of derived facts, and querying for generating Sankey-like flow diagrams that characterize the patient cohorts. We have evaluated the implementation using the real-world MIMIC-III dataset. We discuss the key features of this implementation and direction for future work, which will advance the efforts of the research community for patient cohort identification.
url http://dx.doi.org/10.1155/2020/2851713
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