A Meta-Analysis of Survival Outcomes Following Reoperation in Recurrent Glioblastoma: Time to Consider the Timing of Reoperation

A Meta-Analysis of Survival Outcomes Following Reoperation in Recurrent Glioblastoma: Time to Consider the Timing of Reoperation

Background: Glioblastoma multiforme (GBM) inevitably recurs, but no standard regimen has been established for recurrent patients. Reoperation at recurrence alleviates mass effects, and the survival benefit has been reported in many studies. However, in most studies, the effect of reoperation timing...

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Bibliographic Details
Main Authors: Yu-Hang Zhao, Ze-Fen Wang, Zhi-Yong Pan, Dominik Péus, Juan Delgado-Fernandez, Johan Pallud, Zhi-Qiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neurology
Subjects:
glioblastoma
recurrence
reoperation
time-dependent covariate
survival
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00286/full

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