Advanced Engineering Strategies for Periodontal Complex Regeneration
The regeneration and integration of multiple tissue types is critical for efforts to restore the function of musculoskeletal complex. In particular, the neogenesis of periodontal constructs for systematic tooth-supporting functions is a current challenge due to micron-scaled tissue compartmentalizat...
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doaj-89d63958aae04491b83eaab5022226672020-11-24T20:45:12ZengMDPI AGMaterials1996-19442016-01-01915710.3390/ma9010057ma9010057Advanced Engineering Strategies for Periodontal Complex RegenerationChan Ho Park0Kyoung-Hwa Kim1Yong-Moo Lee2Yang-Jo Seol3Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan 330-714, KoreaDepartment of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul 110-749, KoreaDepartment of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul 110-749, KoreaDepartment of Periodontology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul 110-749, KoreaThe regeneration and integration of multiple tissue types is critical for efforts to restore the function of musculoskeletal complex. In particular, the neogenesis of periodontal constructs for systematic tooth-supporting functions is a current challenge due to micron-scaled tissue compartmentalization, oblique/perpendicular orientations of fibrous connective tissues to the tooth root surface and the orchestration of multiple regenerated tissues. Although there have been various biological and biochemical achievements, periodontal tissue regeneration remains limited and unpredictable. The purpose of this paper is to discuss current advanced engineering approaches for periodontal complex formations; computer-designed, customized scaffolding architectures; cell sheet technology-based multi-phasic approaches; and patient-specific constructs using bioresorbable polymeric material and 3-D printing technology for clinical application. The review covers various advanced technologies for periodontal complex regeneration and state-of-the-art therapeutic avenues in periodontal tissue engineering.http://www.mdpi.com/1996-1944/9/1/57periodontal tissue complexmultiple tissue formationcell sheet engineering3-D printing technology |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chan Ho Park Kyoung-Hwa Kim Yong-Moo Lee Yang-Jo Seol |
spellingShingle |
Chan Ho Park Kyoung-Hwa Kim Yong-Moo Lee Yang-Jo Seol Advanced Engineering Strategies for Periodontal Complex Regeneration Materials periodontal tissue complex multiple tissue formation cell sheet engineering 3-D printing technology |
author_facet |
Chan Ho Park Kyoung-Hwa Kim Yong-Moo Lee Yang-Jo Seol |
author_sort |
Chan Ho Park |
title |
Advanced Engineering Strategies for Periodontal Complex Regeneration |
title_short |
Advanced Engineering Strategies for Periodontal Complex Regeneration |
title_full |
Advanced Engineering Strategies for Periodontal Complex Regeneration |
title_fullStr |
Advanced Engineering Strategies for Periodontal Complex Regeneration |
title_full_unstemmed |
Advanced Engineering Strategies for Periodontal Complex Regeneration |
title_sort |
advanced engineering strategies for periodontal complex regeneration |
publisher |
MDPI AG |
series |
Materials |
issn |
1996-1944 |
publishDate |
2016-01-01 |
description |
The regeneration and integration of multiple tissue types is critical for efforts to restore the function of musculoskeletal complex. In particular, the neogenesis of periodontal constructs for systematic tooth-supporting functions is a current challenge due to micron-scaled tissue compartmentalization, oblique/perpendicular orientations of fibrous connective tissues to the tooth root surface and the orchestration of multiple regenerated tissues. Although there have been various biological and biochemical achievements, periodontal tissue regeneration remains limited and unpredictable. The purpose of this paper is to discuss current advanced engineering approaches for periodontal complex formations; computer-designed, customized scaffolding architectures; cell sheet technology-based multi-phasic approaches; and patient-specific constructs using bioresorbable polymeric material and 3-D printing technology for clinical application. The review covers various advanced technologies for periodontal complex regeneration and state-of-the-art therapeutic avenues in periodontal tissue engineering. |
topic |
periodontal tissue complex multiple tissue formation cell sheet engineering 3-D printing technology |
url |
http://www.mdpi.com/1996-1944/9/1/57 |
work_keys_str_mv |
AT chanhopark advancedengineeringstrategiesforperiodontalcomplexregeneration AT kyounghwakim advancedengineeringstrategiesforperiodontalcomplexregeneration AT yongmoolee advancedengineeringstrategiesforperiodontalcomplexregeneration AT yangjoseol advancedengineeringstrategiesforperiodontalcomplexregeneration |
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1716815124046544896 |