Comparison of performance on neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer's disease patients
Abstract Mild Cognitive Impairment (MCI) can be an intermediate state between normality and dementia in some patients. An early diagnosis, through neuropsychological assessment, could identify individuals at risk of developing dementia. Objective: To verify differences in performance on neuropsycho...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Associação Neurologia Cognitiva e do Comportamento
|
Series: | Dementia & Neuropsychologia |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642009000100041&lng=en&tlng=en |
id |
doaj-89db9acf55c44d1c9948be68888ed7f2 |
---|---|
record_format |
Article |
spelling |
doaj-89db9acf55c44d1c9948be68888ed7f22020-11-24T23:23:21ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-576431414810.1590/S1980-57642009DN30100009S1980-57642009000100041Comparison of performance on neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer's disease patientsPatrícia Helena Figueirêdo do ValeLívia SpíndolaMaira Okada de OliveiraCristiane Garcia da Costa ArmentanoClaudia Sellitto PortoSonia Maria Dozzi BruckiAbstract Mild Cognitive Impairment (MCI) can be an intermediate state between normality and dementia in some patients. An early diagnosis, through neuropsychological assessment, could identify individuals at risk of developing dementia. Objective: To verify differences in performance on neuropsychological tests among controls, amnestic MCI (aMCI) and Alzheimer’s disease (AD) patients. Methods: Sixty-eight AD patients (mean age 73.77±7.24; mean schooling 9.04±4.83; 40 women and 28 men), 34 aMCI patients (mean age 74.44±7.05; mean schooling 12.35±4.01; 20 women) and 60 controls (mean age 68.90±7.48; mean schooling 10.72±4.74; 42 women) were submitted to a neuropsychological assessment composed of tasks assessing executive functions, language, constructive abilities, reasoning and memory. Results: There were statistically significant differences in performance across all tests among control, aMCI and AD groups, and also between only controls and AD patients. On comparing control and aMCI groups, we found statistically significant differences in memory tasks, except for immediate recall of Visual Reproduction. There were also statistically significant differences between aMCI and AD groups on tasks of constructive and visuoperceptual abilities, attention, language and memory, except for delayed recall of Visual Reproduction. Conclusions: Neuropsychological assessment was able to discriminate aMCI from AD patients in almost all tests except for delayed recall of Visual Reproduction, visual organization (Hooper) and executive functions (WCST); and discriminate controls from AD patients in all tests, and controls from aMCI patients in all memory tests except for immediate recall of Visual Reproduction.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642009000100041&lng=en&tlng=enMild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAlzheimer's diseaseneuropsychological testsmemory. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Patrícia Helena Figueirêdo do Vale Lívia Spíndola Maira Okada de Oliveira Cristiane Garcia da Costa Armentano Claudia Sellitto Porto Sonia Maria Dozzi Brucki |
spellingShingle |
Patrícia Helena Figueirêdo do Vale Lívia Spíndola Maira Okada de Oliveira Cristiane Garcia da Costa Armentano Claudia Sellitto Porto Sonia Maria Dozzi Brucki Comparison of performance on neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer's disease patients Dementia & Neuropsychologia Mild Cognitive Impairment Amnestic Mild Cognitive Impairment Alzheimer's disease neuropsychological tests memory. |
author_facet |
Patrícia Helena Figueirêdo do Vale Lívia Spíndola Maira Okada de Oliveira Cristiane Garcia da Costa Armentano Claudia Sellitto Porto Sonia Maria Dozzi Brucki |
author_sort |
Patrícia Helena Figueirêdo do Vale |
title |
Comparison of performance on neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer's disease patients |
title_short |
Comparison of performance on neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer's disease patients |
title_full |
Comparison of performance on neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer's disease patients |
title_fullStr |
Comparison of performance on neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer's disease patients |
title_full_unstemmed |
Comparison of performance on neuropsychological tests in amnestic Mild Cognitive Impairment and Alzheimer's disease patients |
title_sort |
comparison of performance on neuropsychological tests in amnestic mild cognitive impairment and alzheimer's disease patients |
publisher |
Associação Neurologia Cognitiva e do Comportamento |
series |
Dementia & Neuropsychologia |
issn |
1980-5764 |
description |
Abstract Mild Cognitive Impairment (MCI) can be an intermediate state between normality and dementia in some patients. An early diagnosis, through neuropsychological assessment, could identify individuals at risk of developing dementia. Objective: To verify differences in performance on neuropsychological tests among controls, amnestic MCI (aMCI) and Alzheimer’s disease (AD) patients. Methods: Sixty-eight AD patients (mean age 73.77±7.24; mean schooling 9.04±4.83; 40 women and 28 men), 34 aMCI patients (mean age 74.44±7.05; mean schooling 12.35±4.01; 20 women) and 60 controls (mean age 68.90±7.48; mean schooling 10.72±4.74; 42 women) were submitted to a neuropsychological assessment composed of tasks assessing executive functions, language, constructive abilities, reasoning and memory. Results: There were statistically significant differences in performance across all tests among control, aMCI and AD groups, and also between only controls and AD patients. On comparing control and aMCI groups, we found statistically significant differences in memory tasks, except for immediate recall of Visual Reproduction. There were also statistically significant differences between aMCI and AD groups on tasks of constructive and visuoperceptual abilities, attention, language and memory, except for delayed recall of Visual Reproduction. Conclusions: Neuropsychological assessment was able to discriminate aMCI from AD patients in almost all tests except for delayed recall of Visual Reproduction, visual organization (Hooper) and executive functions (WCST); and discriminate controls from AD patients in all tests, and controls from aMCI patients in all memory tests except for immediate recall of Visual Reproduction. |
topic |
Mild Cognitive Impairment Amnestic Mild Cognitive Impairment Alzheimer's disease neuropsychological tests memory. |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642009000100041&lng=en&tlng=en |
work_keys_str_mv |
AT patriciahelenafigueiredodovale comparisonofperformanceonneuropsychologicaltestsinamnesticmildcognitiveimpairmentandalzheimersdiseasepatients AT liviaspindola comparisonofperformanceonneuropsychologicaltestsinamnesticmildcognitiveimpairmentandalzheimersdiseasepatients AT mairaokadadeoliveira comparisonofperformanceonneuropsychologicaltestsinamnesticmildcognitiveimpairmentandalzheimersdiseasepatients AT cristianegarciadacostaarmentano comparisonofperformanceonneuropsychologicaltestsinamnesticmildcognitiveimpairmentandalzheimersdiseasepatients AT claudiasellittoporto comparisonofperformanceonneuropsychologicaltestsinamnesticmildcognitiveimpairmentandalzheimersdiseasepatients AT soniamariadozzibrucki comparisonofperformanceonneuropsychologicaltestsinamnesticmildcognitiveimpairmentandalzheimersdiseasepatients |
_version_ |
1725563890150932480 |