Hop and Acacia Phytochemicals Decreased Lipotoxicity in 3T3-L1 Adipocytes, db/db Mice, and Individuals with Metabolic Syndrome

The plant-based compounds rho-iso-alpha acids (RIAA) from Humulus lupulus (hops) and proanthocyanidins (PAC) from Acacia nilotica have been shown to modulate insulin signaling in vitro. We investigated their effects on triglyceride (TG) deposition in 3T3-L1 adipocytes, glucose and insulin in obese m...

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Bibliographic Details
Main Authors: Deanna M. Minich, Robert H. Lerman, Gary Darland, John G. Babish, Linda M. Pacioretty, Jeffrey S. Bland, Matthew L. Tripp
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Nutrition and Metabolism
Online Access:http://dx.doi.org/10.1155/2010/467316