Cellular and physiological effects of anthrax exotoxin and its relevance to disease
Bacillus anthracis, the causative agent of anthrax, secretes a tripartite exotoxin that exerts pleiotropic effects on the host. The purification of the exotoxin components, protective antigen, lethal factor, and edema factor allowed the rapid characterization of their physiologic effects on the hos...
Main Authors: | David Edward Lowe, Ian Justin Glomski |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-06-01
|
Series: | Frontiers in Cellular and Infection Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00076/full |
Similar Items
-
Innate Immune Interactions between Bacillus anthracis and Host Neutrophils
by: Janet Z. Liu, et al.
Published: (2018-01-01) -
Effets des toxines de Bacillus anthracis sur le cytosquelette des cellules immunitaires : implication sur la phagocytose et les fonctions immunitaires
by: Trescos, Yannick
Published: (2015) -
Immunization of Mice with Anthrax Protective Antigen Limits Cardiotoxicity but Not Hepatotoxicity Following Lethal Toxin Challenge
by: T. Scott Devera, et al.
Published: (2015-06-01) -
Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support
by: Dante A. Suffredini, et al.
Published: (2017-10-01) -
Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies
by: Dante A. Suffredini, et al.
Published: (2015-12-01)