On inotropic effects of UTP in the human heart

On inotropic effects of UTP in the human heart

Uridine 5′-triphosphate (UTP) exerts a positive inotropic effect (PIE) in isolated electrically driven isolated right atrial trabeculae carneae from patients undergoing heart surgery. This review discusses some aspects of the current knowledge on the putative receptor(s) involved and the potential b...

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Bibliographic Details
Main Authors: J. Neumann, B. Hofmann, U. Gergs
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Heliyon
Subjects:
Utp
Inotropy
Human heart
Biochemistry
Pharmacology
P2Y-Receptors
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019358578
Description
Summary:Uridine 5′-triphosphate (UTP) exerts a positive inotropic effect (PIE) in isolated electrically driven isolated right atrial trabeculae carneae from patients undergoing heart surgery. This review discusses some aspects of the current knowledge on the putative receptor(s) involved and the potential biochemical transduction steps leading to the PIE.
ISSN:2405-8440

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