Mutations as Levy flights

Abstract Data from a long time evolution experiment with Escherichia Coli and from a large study on copy number variations in subjects with European ancestry are analyzed in order to argue that mutations can be described as Levy flights in the mutation space. These Levy flights have at least two com...

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Main Authors: Dario A. Leon, Augusto Gonzalez
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88012-1
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spelling doaj-8a0bb5ed6bee48dd81b75449ca296d622021-05-11T14:56:39ZengNature Publishing GroupScientific Reports2045-23222021-05-011111810.1038/s41598-021-88012-1Mutations as Levy flightsDario A. Leon0Augusto Gonzalez1University of Modena & Reggio EmiliaInstitute of Cybernetics, Mathematics and PhysicsAbstract Data from a long time evolution experiment with Escherichia Coli and from a large study on copy number variations in subjects with European ancestry are analyzed in order to argue that mutations can be described as Levy flights in the mutation space. These Levy flights have at least two components: random single-base substitutions and large DNA rearrangements. From the data, we get estimations for the time rates of both events and the size distribution function of large rearrangements.https://doi.org/10.1038/s41598-021-88012-1
collection DOAJ
language English
format Article
sources DOAJ
author Dario A. Leon
Augusto Gonzalez
spellingShingle Dario A. Leon
Augusto Gonzalez
Mutations as Levy flights
Scientific Reports
author_facet Dario A. Leon
Augusto Gonzalez
author_sort Dario A. Leon
title Mutations as Levy flights
title_short Mutations as Levy flights
title_full Mutations as Levy flights
title_fullStr Mutations as Levy flights
title_full_unstemmed Mutations as Levy flights
title_sort mutations as levy flights
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-05-01
description Abstract Data from a long time evolution experiment with Escherichia Coli and from a large study on copy number variations in subjects with European ancestry are analyzed in order to argue that mutations can be described as Levy flights in the mutation space. These Levy flights have at least two components: random single-base substitutions and large DNA rearrangements. From the data, we get estimations for the time rates of both events and the size distribution function of large rearrangements.
url https://doi.org/10.1038/s41598-021-88012-1
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