Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region
The results of retrospective analysis of hemorrhagic fever with renal syndrome (HFRS) incidence in the Perm region for 1995–2009 are shown in the article. There are highly active natural foci of infection on the territory of the region, mainly in the subzone of mixed coniferous-deciduous forests. Fa...
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doaj-8a20626af8a84b41a7ea8a67af1cc4982021-08-02T08:43:15ZrusJournal InfectologyŽurnal Infektologii 2072-67322014-09-0133667310.22625/2072-6732-2011-3-3-66-7358Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm regionM. V. Ivanova0N. N. Vorob’ova1K. V. Shmagel2A. M. Malkova3A. A. Kostarev4The State Medical Academy of Perm named by E.A. Wagner, Perm Regional Hospital of Infectious Diseases, PermThe State Medical Academy of Perm named by E.A. Wagner, PermThe State Medical Academy of Perm named by E.A. Wagner, Perm Institute of Ecology and Genetics of Microorganisms of Ural Branch of the Russian Academy of Sciences, PermTerritorial Service for Surveillance on Consumer Rights Protection and Human Well-being of Perm Region, PermCenter of Hygiene and Epidemiology of Perm region, PermThe results of retrospective analysis of hemorrhagic fever with renal syndrome (HFRS) incidence in the Perm region for 1995–2009 are shown in the article. There are highly active natural foci of infection on the territory of the region, mainly in the subzone of mixed coniferous-deciduous forests. Factors supporting the morbidity are high numbers of small mammals, in particular, the bank vole, with a large circulation of the HFRS virus and active population visit of natural foci in summer-autumn period. Analysis of clinical features of HFRS in 338 patients living in the Perm region, revealed some peculiarities of its course. Among surveyed contingent men (72,4%) prevailed. Most of the patients (80,4%) were of working age (16 to 60 years). More frequently mild and moderate forms (92,8%) of HFRS were observed. A typical picture of the disease with the development of all specific syndromes occurred mainly in patients with severe and moderate forms. Mild cases occurred blurry in the absence of pathognomonic symptoms. Notable was the frequent lesion of liver, with the development of acute anicteric hepatitis (51,2%). Among the complications dominated: pneumonia (4,7%) and acute renal ailure (4,4%). Manifestations of DIC syndrome with recurrent bleeding were registered in 0,6% of patients, toxic shock – at 0,3%. Case fatality rate was 0,6%.https://journal.niidi.ru/jofin/article/view/44hemorrhagic fever with renal syndromeincidence of the diseasepeculiarities of clinical featuresperm region |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
M. V. Ivanova N. N. Vorob’ova K. V. Shmagel A. M. Malkova A. A. Kostarev |
spellingShingle |
M. V. Ivanova N. N. Vorob’ova K. V. Shmagel A. M. Malkova A. A. Kostarev Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region Žurnal Infektologii hemorrhagic fever with renal syndrome incidence of the disease peculiarities of clinical features perm region |
author_facet |
M. V. Ivanova N. N. Vorob’ova K. V. Shmagel A. M. Malkova A. A. Kostarev |
author_sort |
M. V. Ivanova |
title |
Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
title_short |
Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
title_full |
Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
title_fullStr |
Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
title_full_unstemmed |
Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
title_sort |
clinical and epidemiological features of hemorrhagic fever with renal syndrome course in perm region |
publisher |
Journal Infectology |
series |
Žurnal Infektologii |
issn |
2072-6732 |
publishDate |
2014-09-01 |
description |
The results of retrospective analysis of hemorrhagic fever with renal syndrome (HFRS) incidence in the Perm region for 1995–2009 are shown in the article. There are highly active natural foci of infection on the territory of the region, mainly in the subzone of mixed coniferous-deciduous forests. Factors supporting the morbidity are high numbers of small mammals, in particular, the bank vole, with a large circulation of the HFRS virus and active population visit of natural foci in summer-autumn period. Analysis of clinical features of HFRS in 338 patients living in the Perm region, revealed some peculiarities of its course. Among surveyed contingent men (72,4%) prevailed. Most of the patients (80,4%) were of working age (16 to 60 years). More frequently mild and moderate forms (92,8%) of HFRS were observed. A typical picture of the disease with the development of all specific syndromes occurred mainly in patients with severe and moderate forms. Mild cases occurred blurry in the absence of pathognomonic symptoms. Notable was the frequent lesion of liver, with the development of acute anicteric hepatitis (51,2%). Among the complications dominated: pneumonia (4,7%) and acute renal ailure (4,4%). Manifestations of DIC syndrome with recurrent bleeding were registered in 0,6% of patients, toxic shock – at 0,3%. Case fatality rate was 0,6%. |
topic |
hemorrhagic fever with renal syndrome incidence of the disease peculiarities of clinical features perm region |
url |
https://journal.niidi.ru/jofin/article/view/44 |
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