N–3 and n–6 polyunsaturated fatty acids induce cytostasis in human urothelial cells independent of p53 gene function

The role of long-chain polyunsaturated fatty acids (PUFA) in the etiopathology and treatment of cancer is poorly understood. We have studied the effects of n–3 and n–6 PUFA on the proliferation and survival of normal human uroepithelial (NHU) cells, cells with disabled p53 function after stable tran...

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Bibliographic Details
Main Authors: Christine P. Diggle, Eva Pitt, Paul Roberts, Ludwik K. Trejdosiewicz, Jennifer Southgate
Format: Article
Language:English
Published: Elsevier 2000-09-01
Series:Journal of Lipid Research
Subjects:
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334635