Chikungunya fever: Atypical and lethal cases in the Western hemisphere
A large epidemic of Chikungunya fever currently affects the Caribbean, Central and South America. Despite a high number of reported cases, little is known on the occurrence of severe clinical complications. We describe four Venezuelan patients with a severe and/or lethal course who exhibit unusual m...
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doaj-8a2861ca76b54c2b8f3e9f826923508b2021-07-02T06:55:28ZengElsevierIDCases2214-25092015-01-012161010.1016/j.idcr.2014.12.002Chikungunya fever: Atypical and lethal cases in the Western hemisphereJaime R. Torres0Códova G. Leopoldo1Julio S. Castro2Libsen Rodríguez3Víctor Saravia4Joanne Arvelaez5Antonio Ríos-Fabra6María A. Longhi7Melania Marcano8Infectology Section, Tropical Medicine Institute, Universidad Central de Venezuela, Caracas, Bolivarian Republic of VenezuelaInfectology Section, Tropical Medicine Institute, Universidad Central de Venezuela, Caracas, Bolivarian Republic of VenezuelaInfectology Section, Tropical Medicine Institute, Universidad Central de Venezuela, Caracas, Bolivarian Republic of VenezuelaInfectious Diseases Service, Centro Médico Docente La Trinidad, Caracas, Bolivarian Republic of VenezuelaInfectology Section, Tropical Medicine Institute, Universidad Central de Venezuela, Caracas, Bolivarian Republic of VenezuelaClínica RESCARVEN de Chuao, Caracas, Bolivarian Republic of VenezuelaPoliclínica Metropolitana, Caracas, Bolivarian Republic of VenezuelaPoliclínica Metropolitana, Caracas, Bolivarian Republic of VenezuelaClínica RESCARVEN de Chuao, Caracas, Bolivarian Republic of VenezuelaA large epidemic of Chikungunya fever currently affects the Caribbean, Central and South America. Despite a high number of reported cases, little is known on the occurrence of severe clinical complications. We describe four Venezuelan patients with a severe and/or lethal course who exhibit unusual manifestations of the disease. Case 1 describes a 75 year-old man with rapid onset of septic shock and multi-organ failure. Cases 2 and 3 describe two patients with rapid aggressive clinical course who developed shock, severe purpuric lesions and a distinct area large of necrosis in the nasal region. Case 4 depicts a splenectomized woman with shock, generalized purpuric lesions, bullous dermatosis and acronecrosis of an upper limb. Chikungunya fever in the Western hemisphere may also associate with atypical and severe manifestations. Some patients experience a life-threatening, aggressive clinical course, with rapid deterioration and death due to multisystem failure.http://www.sciencedirect.com/science/article/pii/S2214250914000456Chikungunya feverSevereHemorrhagic feverWestern hemisphere |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jaime R. Torres Códova G. Leopoldo Julio S. Castro Libsen Rodríguez Víctor Saravia Joanne Arvelaez Antonio Ríos-Fabra María A. Longhi Melania Marcano |
spellingShingle |
Jaime R. Torres Códova G. Leopoldo Julio S. Castro Libsen Rodríguez Víctor Saravia Joanne Arvelaez Antonio Ríos-Fabra María A. Longhi Melania Marcano Chikungunya fever: Atypical and lethal cases in the Western hemisphere IDCases Chikungunya fever Severe Hemorrhagic fever Western hemisphere |
author_facet |
Jaime R. Torres Códova G. Leopoldo Julio S. Castro Libsen Rodríguez Víctor Saravia Joanne Arvelaez Antonio Ríos-Fabra María A. Longhi Melania Marcano |
author_sort |
Jaime R. Torres |
title |
Chikungunya fever: Atypical and lethal cases in the Western hemisphere |
title_short |
Chikungunya fever: Atypical and lethal cases in the Western hemisphere |
title_full |
Chikungunya fever: Atypical and lethal cases in the Western hemisphere |
title_fullStr |
Chikungunya fever: Atypical and lethal cases in the Western hemisphere |
title_full_unstemmed |
Chikungunya fever: Atypical and lethal cases in the Western hemisphere |
title_sort |
chikungunya fever: atypical and lethal cases in the western hemisphere |
publisher |
Elsevier |
series |
IDCases |
issn |
2214-2509 |
publishDate |
2015-01-01 |
description |
A large epidemic of Chikungunya fever currently affects the Caribbean, Central and South America. Despite a high number of reported cases, little is known on the occurrence of severe clinical complications. We describe four Venezuelan patients with a severe and/or lethal course who exhibit unusual manifestations of the disease.
Case 1 describes a 75 year-old man with rapid onset of septic shock and multi-organ failure. Cases 2 and 3 describe two patients with rapid aggressive clinical course who developed shock, severe purpuric lesions and a distinct area large of necrosis in the nasal region. Case 4 depicts a splenectomized woman with shock, generalized purpuric lesions, bullous dermatosis and acronecrosis of an upper limb.
Chikungunya fever in the Western hemisphere may also associate with atypical and severe manifestations. Some patients experience a life-threatening, aggressive clinical course, with rapid deterioration and death due to multisystem failure. |
topic |
Chikungunya fever Severe Hemorrhagic fever Western hemisphere |
url |
http://www.sciencedirect.com/science/article/pii/S2214250914000456 |
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