Structural and functional properties of genes involved in human cancer
<p>Abstract</p> <p>Background</p> <p>One of the main goals of cancer genetics is to identify the causative elements at the molecular level leading to cancer.</p> <p>Results</p> <p>We have conducted an analysis of a set of genes known to be involv...
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BMC
2006-01-01
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| Series: | BMC Genomics |
| Online Access: | http://www.biomedcentral.com/1471-2164/7/3 |
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doaj-8a3cecd530384979a840b55b217cc19b2020-11-24T22:58:12ZengBMCBMC Genomics1471-21642006-01-0171310.1186/1471-2164-7-3Structural and functional properties of genes involved in human cancerOuzounis Christos AHiggins Desmond GFurney Simon JLópez-Bigas Núria<p>Abstract</p> <p>Background</p> <p>One of the main goals of cancer genetics is to identify the causative elements at the molecular level leading to cancer.</p> <p>Results</p> <p>We have conducted an analysis of a set of genes known to be involved in cancer in order to unveil their unique features that can assist towards the identification of new candidate cancer genes.</p> <p>Conclusion</p> <p>We have detected key patterns in this group of genes in terms of the molecular function or the biological process in which they are involved as well as sequence properties. Based on these features we have developed an accurate Bayesian classification model with which human genes have been scored for their likelihood of involvement in cancer.</p> http://www.biomedcentral.com/1471-2164/7/3 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Ouzounis Christos A Higgins Desmond G Furney Simon J López-Bigas Núria |
| spellingShingle |
Ouzounis Christos A Higgins Desmond G Furney Simon J López-Bigas Núria Structural and functional properties of genes involved in human cancer BMC Genomics |
| author_facet |
Ouzounis Christos A Higgins Desmond G Furney Simon J López-Bigas Núria |
| author_sort |
Ouzounis Christos A |
| title |
Structural and functional properties of genes involved in human cancer |
| title_short |
Structural and functional properties of genes involved in human cancer |
| title_full |
Structural and functional properties of genes involved in human cancer |
| title_fullStr |
Structural and functional properties of genes involved in human cancer |
| title_full_unstemmed |
Structural and functional properties of genes involved in human cancer |
| title_sort |
structural and functional properties of genes involved in human cancer |
| publisher |
BMC |
| series |
BMC Genomics |
| issn |
1471-2164 |
| publishDate |
2006-01-01 |
| description |
<p>Abstract</p> <p>Background</p> <p>One of the main goals of cancer genetics is to identify the causative elements at the molecular level leading to cancer.</p> <p>Results</p> <p>We have conducted an analysis of a set of genes known to be involved in cancer in order to unveil their unique features that can assist towards the identification of new candidate cancer genes.</p> <p>Conclusion</p> <p>We have detected key patterns in this group of genes in terms of the molecular function or the biological process in which they are involved as well as sequence properties. Based on these features we have developed an accurate Bayesian classification model with which human genes have been scored for their likelihood of involvement in cancer.</p> |
| url |
http://www.biomedcentral.com/1471-2164/7/3 |
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