Vitamin A nutritional status in high‐ and low‐income postpartum women and its effect on colostrum and the requirements of the term newborn

• Main Authors: Cristiane Santos Sânzio Gurgel, Evellyn C. Grilo, Larissa Q. Lira, Débora G.F. Assunção, Priscila G. Oliveira, Larisse R.M. de Melo, Silvia V. de Medeiros, Luanna C. Pessanha, Roberto Dimenstein, Clélia O. Lyra
• Format: Article
• Language: Portuguese
• Published: Elsevier 2018-03-01
• Series: Jornal de Pediatria (Versão em Português)
• Subjects: Vitamin A; Colostrum; Postpartum women; High‐income; Low‐income; Newborn
• Online Access: http://www.sciencedirect.com/science/article/pii/S2255553617301489

Objective: To evaluate the vitamin A status in serum and colostrum of postpartum women with different socioeconomic status, comparing the colostrum retinol supply with the vitamin A requirement of the newborn. Methods: Cross-sectional study conducted with 424 postpartum women. Vitamin A maternal dietary intake was estimated using a food frequency questionnaire. Colostrum and serum retinol levels were measured by high performance liquid chromatography (HPLC). Serum retinol concentrations <20 μg/dL were indicative of vitamin A deficiency (VAD). Vitamin A levels provided by colostrum <400 μgRAE/day were considered as insufficient for term newborns. Results: The mean maternal vitamin A intake during pregnancy was 872.2 ± 639.2 μgRAE/day in low-income women and 1169.2 ± 695.2 μgRAE/day for high-income women (p < 0.005). The prevalence of vitamin A deficiency was 6.9% (n = 18) in the low-income group and 3.7% (n = 6) in the high-income group. The estimated mean retinol intake by infants of the high- and low-income mothers were 343.3 μgRAE/day (85.8% AI) and 427.2 μgRAE/day (106.8% AI), respectively. Conclusions: Serum vitamin A deficiency was considered a mild public health problem in both populations; however, newborns of low‐income women were more likely to receive lower retinol levels through colostrum when compared with newborns of high‐income mothers.