Th1- and Th17-Related Cytokines in Venous and Arterial Blood of Sclerodermic Patients with and without Digital Ulcers
The earliest clinical manifestation of SSc is usually Raynaud’s phenomenon, a small-arteries vasospasm driven by vascular tone dysregulation and microcirculatory abnormalities, resulting in digital ulcers (DU) in up to 50% of patients. Many cytokines as well as growth factors have been shown to play...
Main Authors: | S. Nicola, M. Fornero, E. Fusaro, C. Peroni, M. Priora, G. Rolla, C. Bucca, L. Brussino |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2019-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2019/7908793 |
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