Too much of a good thing
A mutation that causes heart disease in humans increases the number of active myosin heads during muscle contraction in fruit flies, leading to the progressive dysfunction of the flight muscles and heart tube.
Main Author: | H Lee Sweeney |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-09-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/41178 |
Similar Items
-
Prolonged cross-bridge binding triggers muscle dysfunction in a Drosophila model of myosin-based hypertrophic cardiomyopathy
by: William A Kronert, et al.
Published: (2018-08-01) -
Noncovalent Crosslinking of SH1 and SH2 to Detect Dynamic Flexibility of the SH1 Helix
by: Park, Hyunguk
Published: (2000) -
Impact of Anti-S2 Peptides on a Variety of Muscle Myosin S2 Isoforms and Hypertrophic Cardiomyopathy Mutants Revealed by Fluorescence Resonance Energy Transfer and Gravitational Force Spectroscopy
by: Aboonasrshiraz, Negar
Published: (2020) -
Neuroregulation and Myosin Light Chain Phosphorylation in Ascaris Suum Obliquely Striated Skeletal Muscle
by: Martin, Rex E. (Rex Edward)
Published: (1985) -
Myosin-based regulation of twitch and tetanic contractions in mammalian skeletal muscle
by: Cameron Hill, et al.
Published: (2021-06-01)