5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores.

The contribution of 5α-reductase 1 and 5α-reductase 2 to prostate cancer development and progression is not clearly understood. TRAMP mice are a common prostate cancer model, in which 5α-reductase 1 and 5α-reductase 2 expression levels, along with prostate lesions scores, have not been investigated...

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Bibliographic Details
Main Authors: Alexander B Opoku-Acheampong, Jamie N Henningson, Amanda P Beck, Brian L Lindshield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5426600?pdf=render

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