Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo

Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo

Summary: Human DNA polymerase delta (Pol δ) forms a holoenzyme complex with the DNA sliding clamp proliferating cell nuclear antigen (PCNA) to perform its essential roles in genome replication. Here, we utilize live-cell single-molecule tracking to monitor Pol δ holoenzyme interaction with the genom...

Full description

Bibliographic Details
Main Authors:	William C. Drosopoulos, David A. Vierra, Charles A. Kenworthy, Robert A. Coleman, Carl L. Schildkraut
Format:	Article
Language:	English
Published:	Elsevier 2020-02-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124719317668

Similar Items

Stepwise assembly of the human replicative polymerase holoenzyme
by: Mark Hedglin, et al.
Published: (2013-04-01)

Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
by: Jiangyu Yan, et al.
Published: (2017-05-01)

Live-Cell Analysis of Human Cytomegalovirus DNA Polymerase Holoenzyme Assembly by Resonance Energy Transfer Methods
by: Veronica Di Antonio, et al.
Published: (2021-04-01)

Structure of the processive human Pol δ holoenzyme
by: Claudia Lancey, et al.
Published: (2020-02-01)

RNA polymerase II holoenzyme components and regulation
by: Wilson, Christopher J. (Christopher John), 1971-
Published: (2014)

Yeast and mammalian RNA polymerase II holoenzymes
by: Chao, David M. (David Min)
Published: (2008)

Promoter DNA Melting by RNA Polymerase Holoenzyme Containing Various Sigma Factors
by: Li, Tianzi, li
Published: (2016)

Collision with duplex DNA renders Escherichia coli DNA polymerase III holoenzyme susceptible to DNA polymerase IV-mediated polymerase switching on the sliding clamp
by: Thanh Thi Le, et al.
Published: (2017-10-01)

Regulation of yeast RNA polymerase II holoenzyme transcription
by: Hengartner, Christoph J. (Christopher Johannes), 1968-
Published: (2014)

Structure of a bacterial RNA polymerase holoenzyme open promoter complex
by: Brian Bae, et al.
Published: (2015-09-01)

RNA polymerase II holoenzyme-mediated regulation of GAL4
by: Hirst, John Martin
Published: (2009)

RNA polymerase II holoenzyme-mediated regulation of GAL4
by: Hirst, John Martin
Published: (2009)

Functional antagonism of the RNA polymerase II holoenzyme by negative regulators
by: Gadbois, Ellen L. (Ellen Louise), 1968-
Published: (2008)

The Pseudorabies Virus DNA Polymerase Accessory Subunit UL42 Directs Nuclear Transport of the Holoenzyme
by: Yi-Ping eWang, et al.
Published: (2016-02-01)

Single molecule studies of the telomerase holoenzyme assembly and DNA G-quadruplex unfolding
by: Ashbridge, Beth
Published: (2011)

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ
by: Tsuda, Masataka
Published: (2017)

Domain Structures and Inter-Domain Interactions Defining the Holoenzyme Architecture of Archaeal D-Family DNA Polymerase
by: Hideshi Yokoyama, et al.
Published: (2013-07-01)

Proteomics of RNA polymerase II holoenzymes during P19 cardiomyogenesis
by: Maes Olivier
Published: (2007-12-01)

Molecular genetic analysis of a yeast RNA polymerase II holoenzyme
by: Thompson, Craig Marshall
Published: (2006)

Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome
by: Zuanning Yuan, et al.
Published: (2020-06-01)

Mechanism of Polydenylate-Polyuridylate Synthesis by RNA Polymerase Holoenzyme II of Escherichia coli
by: Iwakura, Yoichiro
Published: (2009)

Integrated Product Design for Assembly and Disassembly and Assembly and Disassembly Sequence Planning
by: Shin-Huei Chiou, et al.

Correction: The Whole Set of Constitutive Promoters Recognized by RNA Polymerase RpoD Holoenzyme of.
Published: (2014-01-01)

Regulation of the RNA polymerase II holoenzyme-associated cyclin-dependent kinase SRB10
by: Goto, Susan Lisa
Published: (2009)

Regulation of the RNA polymerase II holoenzyme-associated cyclin-dependent kinase SRB10
by: Goto, Susan Lisa
Published: (2009)

Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain.
by: Céline Contesto-Richefeu, et al.
Published: (2014-03-01)

Java Assembler and Disassembler
by: Kuan-Ming Twu, et al.

Generation of active protein phosphatase 2A is coupled to holoenzyme assembly.
by: Hans Hombauer, et al.
Published: (2007-06-01)

The whole set of constitutive promoters recognized by RNA polymerase RpoD holoenzyme of Escherichia coli.
by: Tomohiro Shimada, et al.
Published: (2014-01-01)

AUTOMATIC SUB-ASSEMBLY DETECTION, DISASSEMBLY SEQUENCING AND DISASSEMBLY DIRECTION PREDICTOR FOR AN ASSEMBLY MODEL
by: SHANMUGAM, SIVAMOORTHY
Published: (2005)

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
by: Zhi-Xiong Zhou, et al.
Published: (2019-09-01)

The assembly and disassembly of clathrin cages
by: Baker, Michael
Published: (2016)

Correction: The Whole Set of Constitutive Promoters Recognized by RNA Polymerase RpoD Holoenzyme of Escherichia coli
by: The Staff
Published: (2014-01-01)

Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
by: Simona Ranallo, et al.
Published: (2019-12-01)

ChIP-exo interrogation of Crp, DNA, and RNAP holoenzyme interactions.
by: Haythem Latif, et al.
Published: (2018-01-01)

DNA Polymerase B1 Binding Protein 1 Is Important for DNA Repair by Holoenzyme PolB1 in the Extremely Thermophilic Crenarchaeon <i>Sulfolobus acidocaldarius</i>
by: Hiroka Miyabayashi, et al.
Published: (2021-02-01)

Transcription of Ehrlichia chaffeensis genes is accomplished by RNA polymerase holoenzyme containing either sigma 32 or sigma 70.
by: Huitao Liu, et al.
Published: (2013-01-01)

Role of Translesion Synthesis DNA Polymerases in DNA Replication in the Presence of a Weak DNA Polymerase δ in Saccharomyces cerevisiae
by: Likui Zhang, et al.
Published: (2018-02-01)

The Analysis of the Disassembly Sequece and Displacement for an assembly
by: David Chen, et al.
Published: (2001)

The Study of the Design of Green Assembly and Disassembly
by: Syeh, jih-her, et al.
Published: (1999)