Investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver disease

Background: Non-alcoholic fatty liver disease (NAFLD) is very common and serious disease. It begins as a simple hepatosteatosis but can progress to cirrhosis. The early detection of portal hypertension (HT) can be helpful in the management of these patients. Aims: To evaluate radiologic findings of...

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Main Authors: Fatma Kulali, Burcu Kaya-Tuna, Aslihan Semiz-Oysu, Zeynep Gamze Kilicoglu, Yasar Bukte
Format: Article
Language:English
Published: SpringerOpen 2016-09-01
Series:The Egyptian Journal of Radiology and Nuclear Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0378603X16300717
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spelling doaj-8aae1dd7c2cd4825950edde42590f7ae2020-11-25T01:50:36ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2016-09-0147370771010.1016/j.ejrnm.2016.05.012Investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver diseaseFatma Kulali0Burcu Kaya-Tuna1Aslihan Semiz-Oysu2Zeynep Gamze Kilicoglu3Yasar Bukte4Umraniye Training and Research Hospital, Istanbul, TurkeyUmraniye Training and Research Hospital, Istanbul, TurkeyUmraniye Training and Research Hospital, Istanbul, TurkeyHaydarpasa Numune Training and Research Hospital, Istanbul, TurkeyUmraniye Training and Research Hospital, Istanbul, TurkeyBackground: Non-alcoholic fatty liver disease (NAFLD) is very common and serious disease. It begins as a simple hepatosteatosis but can progress to cirrhosis. The early detection of portal hypertension (HT) can be helpful in the management of these patients. Aims: To evaluate radiologic findings of portal hypertension at computed tomography (CT) of patients with non-alcoholic fatty liver disease for early diagnosis. Methods and materials: Images of 225 cases who underwent non-enhanced abdominal CT were reviewed. The patients with the difference between hepatic and splenic attenuation (CT L-S) > 10 were enrolled in hepatosteatosis group. The remainings formed control group. The relationship between two groups about diameters of portal and splenic veins, craniocaudal (CC) span of liver, splenic index, caudate lobe/right lobe (C/RL) ratio was analyzed statistically by Mann–Whitney U Test and Student’s t-test. Results: Total 213 cases, as hepatosteatosis (n = 149) and control (n = 64) groups, were involved in this study. Liver CC span, splenic index and C/RL ratio between two groups were found to be statistically significant (p < 0.01). Conclusions: The splenic index and C/RL ratio are important findings of portal HT and fibrosis. CT imaging can be beneficial for diagnosis and treatment of NAFLD patients.http://www.sciencedirect.com/science/article/pii/S0378603X16300717HepatosteatosisPortal hypertensionFatty liverCirrhosis
collection DOAJ
language English
format Article
sources DOAJ
author Fatma Kulali
Burcu Kaya-Tuna
Aslihan Semiz-Oysu
Zeynep Gamze Kilicoglu
Yasar Bukte
spellingShingle Fatma Kulali
Burcu Kaya-Tuna
Aslihan Semiz-Oysu
Zeynep Gamze Kilicoglu
Yasar Bukte
Investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver disease
The Egyptian Journal of Radiology and Nuclear Medicine
Hepatosteatosis
Portal hypertension
Fatty liver
Cirrhosis
author_facet Fatma Kulali
Burcu Kaya-Tuna
Aslihan Semiz-Oysu
Zeynep Gamze Kilicoglu
Yasar Bukte
author_sort Fatma Kulali
title Investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver disease
title_short Investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver disease
title_full Investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver disease
title_fullStr Investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver disease
title_full_unstemmed Investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver disease
title_sort investigation of computed tomography findings of portal hypertension at non-alcoholic fatty liver disease
publisher SpringerOpen
series The Egyptian Journal of Radiology and Nuclear Medicine
issn 0378-603X
publishDate 2016-09-01
description Background: Non-alcoholic fatty liver disease (NAFLD) is very common and serious disease. It begins as a simple hepatosteatosis but can progress to cirrhosis. The early detection of portal hypertension (HT) can be helpful in the management of these patients. Aims: To evaluate radiologic findings of portal hypertension at computed tomography (CT) of patients with non-alcoholic fatty liver disease for early diagnosis. Methods and materials: Images of 225 cases who underwent non-enhanced abdominal CT were reviewed. The patients with the difference between hepatic and splenic attenuation (CT L-S) > 10 were enrolled in hepatosteatosis group. The remainings formed control group. The relationship between two groups about diameters of portal and splenic veins, craniocaudal (CC) span of liver, splenic index, caudate lobe/right lobe (C/RL) ratio was analyzed statistically by Mann–Whitney U Test and Student’s t-test. Results: Total 213 cases, as hepatosteatosis (n = 149) and control (n = 64) groups, were involved in this study. Liver CC span, splenic index and C/RL ratio between two groups were found to be statistically significant (p < 0.01). Conclusions: The splenic index and C/RL ratio are important findings of portal HT and fibrosis. CT imaging can be beneficial for diagnosis and treatment of NAFLD patients.
topic Hepatosteatosis
Portal hypertension
Fatty liver
Cirrhosis
url http://www.sciencedirect.com/science/article/pii/S0378603X16300717
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