Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

Parkinson’s disease (PD) is a common neurodegenerative disorder with a complex etiology involving genetics and the environment. Here, Vallerga et al. identify two CpG probes associated with PD in a blood cell type-corrected epigenome-wide meta-analysis, implicating the SLC7A11 gene as a plausible bi...

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Bibliographic Details
Main Authors: Costanza L. Vallerga, Futao Zhang, Javed Fowdar, Allan F. McRae, Ting Qi, Marta F. Nabais, Qian Zhang, Irfahan Kassam, Anjali K. Henders, Leanne Wallace, Grant Montgomery, Yu-Hsuan Chuang, Steve Horvath, Beate Ritz, Glenda Halliday, Ian Hickie, John B. Kwok, John Pearson, Toni Pitcher, Martin Kennedy, Steven R. Bentley, Peter A. Silburn, Jian Yang, Naomi R. Wray, Simon J. G. Lewis, Tim Anderson, John Dalrymple-Alford, George D. Mellick, Peter M. Visscher, Jacob Gratten
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15065-7

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