Highly sensitive detection of estradiol by a SERS sensor based on TiO2 covered with gold nanoparticles
We propose the use of gold nanoparticles grown on the surface of nanoporous TiO2 films as surface-enhanced Raman scattering (SERS) sensors for the detection of 17β-estradiol. Gold deposition on top of a TiO2 surface leads to the formation of nanoparticles the plasmonic properties of which fulfil the...
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doaj-8ac24a72ac1c48e3bc9194c67b01effd2020-11-25T03:45:52ZengBeilstein-InstitutBeilstein Journal of Nanotechnology2190-42862020-07-011111026103510.3762/bjnano.11.872190-4286-11-87Highly sensitive detection of estradiol by a SERS sensor based on TiO2 covered with gold nanoparticlesAndrea Brognara0Ili F. Mohamad Ali Nasri1Beatrice R. Bricchi2Andrea Li Bassi3Caroline Gauchotte-Lindsay4Matteo Ghidelli5Nathalie Lidgi-Guigui6Dipartimento di Energia, Laboratorio Materiali Micro e Nanostrutturati, Politecnico di Milano, via Ponzio 34/3, I-20133 Milano, ItalyJames Watt School of Engineering, Rankine Building, Oakfield Avenue, G12 8LT, University of Glasgow, Glasgow, United KingdomDipartimento di Energia, Laboratorio Materiali Micro e Nanostrutturati, Politecnico di Milano, via Ponzio 34/3, I-20133 Milano, ItalyDipartimento di Energia, Laboratorio Materiali Micro e Nanostrutturati, Politecnico di Milano, via Ponzio 34/3, I-20133 Milano, ItalyJames Watt School of Engineering, Rankine Building, Oakfield Avenue, G12 8LT, University of Glasgow, Glasgow, United KingdomDipartimento di Energia, Laboratorio Materiali Micro e Nanostrutturati, Politecnico di Milano, via Ponzio 34/3, I-20133 Milano, Italynow at Laboratoire des Sciences des Procédés et des Matériaux (LSPM), CNRS, Université Sorbonne Paris Nord, 93430, Villetaneuse, FranceWe propose the use of gold nanoparticles grown on the surface of nanoporous TiO2 films as surface-enhanced Raman scattering (SERS) sensors for the detection of 17β-estradiol. Gold deposition on top of a TiO2 surface leads to the formation of nanoparticles the plasmonic properties of which fulfil the requirements of a SERS sensor. The morphological and optical properties of the surface were investigated. Specifically, we demonstrate that the TiO2 background pressure during pulsed laser deposition and the annealing conditions offer control over the formation of Au nanoparticles with different sizes, shapes and distributions, yielding a versatile sensor. We have exploited the surface for the detection of 17β-estradiol, an emerging contaminant in environmental waters. We have found a limit of detection of 1 nM with a sensitivity allowing for a dynamic range of five orders of magnitude (up to 100 µM).https://doi.org/10.3762/bjnano.11.87aptamerau nanoparticles17-β estradiol (e2)plasmonicssensorsurface-enhanced raman scattering (sers)tio2 nanostructures |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Andrea Brognara Ili F. Mohamad Ali Nasri Beatrice R. Bricchi Andrea Li Bassi Caroline Gauchotte-Lindsay Matteo Ghidelli Nathalie Lidgi-Guigui |
spellingShingle |
Andrea Brognara Ili F. Mohamad Ali Nasri Beatrice R. Bricchi Andrea Li Bassi Caroline Gauchotte-Lindsay Matteo Ghidelli Nathalie Lidgi-Guigui Highly sensitive detection of estradiol by a SERS sensor based on TiO2 covered with gold nanoparticles Beilstein Journal of Nanotechnology aptamer au nanoparticles 17-β estradiol (e2) plasmonics sensor surface-enhanced raman scattering (sers) tio2 nanostructures |
author_facet |
Andrea Brognara Ili F. Mohamad Ali Nasri Beatrice R. Bricchi Andrea Li Bassi Caroline Gauchotte-Lindsay Matteo Ghidelli Nathalie Lidgi-Guigui |
author_sort |
Andrea Brognara |
title |
Highly sensitive detection of estradiol by a SERS sensor based on TiO2 covered with gold nanoparticles |
title_short |
Highly sensitive detection of estradiol by a SERS sensor based on TiO2 covered with gold nanoparticles |
title_full |
Highly sensitive detection of estradiol by a SERS sensor based on TiO2 covered with gold nanoparticles |
title_fullStr |
Highly sensitive detection of estradiol by a SERS sensor based on TiO2 covered with gold nanoparticles |
title_full_unstemmed |
Highly sensitive detection of estradiol by a SERS sensor based on TiO2 covered with gold nanoparticles |
title_sort |
highly sensitive detection of estradiol by a sers sensor based on tio2 covered with gold nanoparticles |
publisher |
Beilstein-Institut |
series |
Beilstein Journal of Nanotechnology |
issn |
2190-4286 |
publishDate |
2020-07-01 |
description |
We propose the use of gold nanoparticles grown on the surface of nanoporous TiO2 films as surface-enhanced Raman scattering (SERS) sensors for the detection of 17β-estradiol. Gold deposition on top of a TiO2 surface leads to the formation of nanoparticles the plasmonic properties of which fulfil the requirements of a SERS sensor. The morphological and optical properties of the surface were investigated. Specifically, we demonstrate that the TiO2 background pressure during pulsed laser deposition and the annealing conditions offer control over the formation of Au nanoparticles with different sizes, shapes and distributions, yielding a versatile sensor. We have exploited the surface for the detection of 17β-estradiol, an emerging contaminant in environmental waters. We have found a limit of detection of 1 nM with a sensitivity allowing for a dynamic range of five orders of magnitude (up to 100 µM). |
topic |
aptamer au nanoparticles 17-β estradiol (e2) plasmonics sensor surface-enhanced raman scattering (sers) tio2 nanostructures |
url |
https://doi.org/10.3762/bjnano.11.87 |
work_keys_str_mv |
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