The Role of P2X7 Receptor in Alzheimer’s Disease

The Role of P2X7 Receptor in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease characterized by a progressive cognitive decline associated with global brain damage. Initially, intracellular paired helical filaments composed by hyperphosphorylated tau and extracellular deposits of amyloid-β (Aβ) were postu...

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Bibliographic Details
Main Authors:	Linda Francistiová, Carolina Bianchi, Caterina Di Lauro, Álvaro Sebastián-Serrano, Laura de Diego-García, Julianna Kobolák, András Dinnyés, Miguel Díaz-Hernández
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-06-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	amyloidogenic processing inflammation oxidative stress synaptopathy microglia induced pluripotent stem cells
Online Access:	https://www.frontiersin.org/article/10.3389/fnmol.2020.00094/full

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