Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence

Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence

Early stress is a significant risk factor for the onset of mood disorders such as depression during adulthood. Impairments in cognitive flexibility mediated by prefrontal cortex (PFC) dysfunction are increasingly recognized as important etiological and pathological factors in the development of depr...

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Bibliographic Details
Main Authors:	Hang Xu, Yu Zhang, Fan Zhang, Sanna Yuan, Feng Shao, Weiwen Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-10-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	Adolescent social stress Brain-derived neurotrophic factor (BDNF) cognitive flexibility medial prefrontal cortex (mPFC)
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00095/full

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