Intracellular tracing of amyloid vaccines through direct fluorescent labelling
Abstract Alzheimer’s disease is a debilitating neurodegenerative condition that progressively causes synaptic loss and major neuronal damage. Immunotherapy utilising Aβ as an active immunogen or via passive treatment utilising antibodies raised to amyloid have shown therapeutic promise. The migrator...
Main Authors: | Matthew Mold, Manpreet Kumar, Ambreen Mirza, Emma Shardlow, Christopher Exley |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-20845-9 |
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