Modelling cardiac fibrosis using three-dimensional cardiac microtissues derived from human embryonic stem cells

Modelling cardiac fibrosis using three-dimensional cardiac microtissues derived from human embryonic stem cells

Abstract Background Cardiac fibrosis is the most common pathway of many cardiac diseases. To date, there has been no suitable in vitro cardiac fibrosis model that could sufficiently mimic the complex environment of the human heart. Here, a three-dimensional (3D) cardiac sphere platform of contractil...

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Bibliographic Details
Main Authors: Mi-Ok Lee, Kwang Bo Jung, Seong-Jae Jo, Sung-Ae Hyun, Kyoung-Sik Moon, Joung-Wook Seo, Sang-Heon Kim, Mi-Young Son
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Biological Engineering
Subjects:
Cardiac fibrosis
Cardiac sphere
Cardiac microtissue
Cardiomyocyte
Mesenchymal stem cell
Online Access:http://link.springer.com/article/10.1186/s13036-019-0139-6

Internet

http://link.springer.com/article/10.1186/s13036-019-0139-6

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