Modelling cardiac fibrosis using three-dimensional cardiac microtissues derived from human embryonic stem cells
Abstract Background Cardiac fibrosis is the most common pathway of many cardiac diseases. To date, there has been no suitable in vitro cardiac fibrosis model that could sufficiently mimic the complex environment of the human heart. Here, a three-dimensional (3D) cardiac sphere platform of contractil...
Main Authors: | Mi-Ok Lee, Kwang Bo Jung, Seong-Jae Jo, Sung-Ae Hyun, Kyoung-Sik Moon, Joung-Wook Seo, Sang-Heon Kim, Mi-Young Son |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-02-01
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Series: | Journal of Biological Engineering |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13036-019-0139-6 |
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