The NADPH Oxidase Nox4 Controls Macrophage Polarization in an NFκB-Dependent Manner

The family of NADPH oxidases represents an important source of reactive oxygen species (ROS) within the cell. Nox4 is a special member of this family as it constitutively produces H2O2 and its loss promotes inflammation. A major cellular component of inflammation is the macrophage population, which...

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Bibliographic Details
Main Authors: V. Helfinger, K. Palfi, A. Weigert, K. Schröder
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/3264858

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