The age-dependent effects of a single-dose methylphenidate challenge on cerebral perfusion in patients with attention-deficit/hyperactivity disorder

The age-dependent effects of a single-dose methylphenidate challenge on cerebral perfusion in patients with attention-deficit/hyperactivity disorder

Methylphenidate (MPH) is a stimulant drug and an effective treatment for attention-deficit/hyperactivity disorder (ADHD) in both children and adults. Pre-clinical studies suggest that the response to stimulants is dependent on age, which may reflect the ontogeny of the dopamine (DA) system, which co...

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Bibliographic Details
Main Authors:	A Schrantee, HJMM Mutsaerts, C Bouziane, HGH Tamminga, MA Bottelier, L Reneman
Format:	Article
Language:	English
Published:	Elsevier 2017-01-01
Series:	NeuroImage: Clinical
Subjects:	ADHD Methylphenidate Dopamine Age Cerebral blood flow Arterial spin labeling
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213158216302297

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