Single-Cell Sequencing Confirms Transcripts and V<sub>H</sub>DJ<sub>H</sub> Rearrangements of Immunoglobulin Genes in Human Podocytes

Single-Cell Sequencing Confirms Transcripts and V<sub>H</sub>DJ<sub>H</sub> Rearrangements of Immunoglobulin Genes in Human Podocytes

Most glomerular diseases are associated with inflammation caused by deposited pathogenic immunoglobulins (Igs), which are believed to be produced by B cells. However, our previous study indicated that the human podocyte cell line can produce IgG. In this study, we aimed to confirm the transcripts an...

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Bibliographic Details
Main Authors: Zhenling Deng, Huige Yan, Zhan Shi, Xinyu Tian, Zhuan Cui, Yingchun Sun, Song Wang, Danxia Zheng, Xiaoyan Qiu, Yue Wang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Genes
Subjects:
podocyte
single-cell RNA sequencing
immunoglobulins
gene transcription
V<sub>H</sub>DJ<sub>H</sub> rearrangement
Online Access:https://www.mdpi.com/2073-4425/12/4/472

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