Targeting β-cell dedifferentiation and transdifferentiation: opportunities and challenges
The most distinctive pathological characteristics of diabetes mellitus induced by various stressors or immune-mediated injuries are reductions of pancreatic islet β-cell populations and activity. Existing treatment strategies cannot slow disease progression; consequently, research to genetically eng...
Main Authors: | Wenrui Wang, Chuan Zhang |
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Format: | Article |
Language: | English |
Published: |
Bioscientifica
2021-08-01
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Series: | Endocrine Connections |
Subjects: | |
Online Access: | https://ec.bioscientifica.com/view/journals/ec/10/8/EC-21-0260.xml |
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