High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions
Background: The Panax ginseng plant is used as an herbal medicine. Phytosterols of P. ginseng have inhibitory effects on inflammation-related factors in HepG2 cells. Methods: Phytosterols (e.g., stigmasterol and β-sitosterol) in the roots of P. ginseng grown under various conditions were analyzed us...
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doaj-8b4ca97b4ff94d449626e99240ec249e2020-11-24T20:59:58ZengElsevierJournal of Ginseng Research1226-84532018-01-01421162010.1016/j.jgr.2016.10.004High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditionsDong Gu Lee0Jaemin Lee1Kyung-Tack Kim2Sang-Won Lee3Young-Ock Kim4Ik-Hyun Cho5Hak-Jae Kim6Chun-Gun Park7Sanghyun Lee8Department of Integrative Plant Science, Chung-Ang University, Anseong, Republic of KoreaDepartment of Integrative Plant Science, Chung-Ang University, Anseong, Republic of KoreaKorea Food Research Institute, Sungnam, Republic of KoreaDepartment of Medicinal Crop Research Institute, National Institute of Horticultural and Herbal Science, Rural Development Administration, Eumseong, Republic of KoreaDepartment of Medicinal Crop Research Institute, National Institute of Horticultural and Herbal Science, Rural Development Administration, Eumseong, Republic of KoreaDepartment of Convergence Medical Science, Brain Korea 21 Plus Program, and Institute of Korean Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, Republic of KoreaDepartment of Clinical Pharmacology, College of Medicine, Soonchunhyang University, Cheonan, Republic of KoreaDepartment of Medicinal Crop Research Institute, National Institute of Horticultural and Herbal Science, Rural Development Administration, Eumseong, Republic of KoreaDepartment of Integrative Plant Science, Chung-Ang University, Anseong, Republic of KoreaBackground: The Panax ginseng plant is used as an herbal medicine. Phytosterols of P. ginseng have inhibitory effects on inflammation-related factors in HepG2 cells. Methods: Phytosterols (e.g., stigmasterol and β-sitosterol) in the roots of P. ginseng grown under various conditions were analyzed using high-performance liquid chromatography. The P. ginseng roots analyzed in this study were collected from three cultivation areas in Korea (i.e., Geumsan, Yeongju, and Jinan) and differed by cultivation year (i.e., 4 years, 5 years, and 6 years) and production process (i.e., straight ginseng, red ginseng, and white ginseng). Results: The concentrations of stigmasterol and β-sitosterol in P. ginseng roots were 2.22–23.04 mg/g and 7.35–59.09 mg/g, respectively. The highest concentrations of stigmasterol and β-sitosterol were in the roots of 6-year-old P. ginseng cultivated in Jinan (82.14 mg/g and 53.23 mg/g, respectively). Conclusion: Six-year-old white ginseng and white ginseng cultivated in Jinan containing stigmasterol and β-sitosterol are potentially a new source of income in agriculture.http://www.sciencedirect.com/science/article/pii/S1226845316300550Panax ginsengquantitative analysisrootsterol |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dong Gu Lee Jaemin Lee Kyung-Tack Kim Sang-Won Lee Young-Ock Kim Ik-Hyun Cho Hak-Jae Kim Chun-Gun Park Sanghyun Lee |
spellingShingle |
Dong Gu Lee Jaemin Lee Kyung-Tack Kim Sang-Won Lee Young-Ock Kim Ik-Hyun Cho Hak-Jae Kim Chun-Gun Park Sanghyun Lee High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions Journal of Ginseng Research Panax ginseng quantitative analysis root sterol |
author_facet |
Dong Gu Lee Jaemin Lee Kyung-Tack Kim Sang-Won Lee Young-Ock Kim Ik-Hyun Cho Hak-Jae Kim Chun-Gun Park Sanghyun Lee |
author_sort |
Dong Gu Lee |
title |
High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions |
title_short |
High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions |
title_full |
High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions |
title_fullStr |
High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions |
title_full_unstemmed |
High-performance liquid chromatography analysis of phytosterols in Panax ginseng root grown under different conditions |
title_sort |
high-performance liquid chromatography analysis of phytosterols in panax ginseng root grown under different conditions |
publisher |
Elsevier |
series |
Journal of Ginseng Research |
issn |
1226-8453 |
publishDate |
2018-01-01 |
description |
Background: The Panax ginseng plant is used as an herbal medicine. Phytosterols of P. ginseng have inhibitory effects on inflammation-related factors in HepG2 cells.
Methods: Phytosterols (e.g., stigmasterol and β-sitosterol) in the roots of P. ginseng grown under various conditions were analyzed using high-performance liquid chromatography. The P. ginseng roots analyzed in this study were collected from three cultivation areas in Korea (i.e., Geumsan, Yeongju, and Jinan) and differed by cultivation year (i.e., 4 years, 5 years, and 6 years) and production process (i.e., straight ginseng, red ginseng, and white ginseng).
Results: The concentrations of stigmasterol and β-sitosterol in P. ginseng roots were 2.22–23.04 mg/g and 7.35–59.09 mg/g, respectively. The highest concentrations of stigmasterol and β-sitosterol were in the roots of 6-year-old P. ginseng cultivated in Jinan (82.14 mg/g and 53.23 mg/g, respectively).
Conclusion: Six-year-old white ginseng and white ginseng cultivated in Jinan containing stigmasterol and β-sitosterol are potentially a new source of income in agriculture. |
topic |
Panax ginseng quantitative analysis root sterol |
url |
http://www.sciencedirect.com/science/article/pii/S1226845316300550 |
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